BRSK1 antibody
Principal name
BRSK1 antibody
Alternative names for BRSK1 antibody
KIAA1811, SAD1, SAD-B, BR serine/threonine-protein kinase 1, SAD1 kinase, Serine/threonine kinase SAD-B
Ncbi ID
9606, NP_115806.1, NM_032430, Q8TDC3, NP_001003920.2, NM_001003920
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of BRSK1 antibody
BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. BRSK1 is unbiquitously expressed, with highest levels of expression in the brain and testes. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function. More recently, it has been shown that both BRSK1 and the related protein BRSK2 are required for mammalian neuronal polarization. While BRSK1- and BRSK2-null mice were viable, double-mutant mice died within two hours of birth. Neurons from these mice showed uniformly-sized neurites as opposed to the normal long axon and multiple shorter dendrites. These neurites also displayed both axonal and dendritic markers. At least two isoforms of BRSK1 are known to exist.








Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA306410 | BRSK1 (C-term) antibody |
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Rabbit Polyclonal BRSK1 Antibody | |||||||
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Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, P, WB |
0.1 mg /
€415.00
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|
OriGene Technologies, Inc. | |||||||
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TA306411 | BRSK1 (Center) antibody |
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Rabbit Polyclonal BRSK1 Antibody | |||||||
![]() |
Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, P, WB |
0.1 mg /
€415.00
|
|
OriGene Technologies, Inc. | |||||||
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