BTBD12 antibody

Principal name

BTBD12 antibody

Alternative names for BTBD12 antibody

KIAA1784, KIAA1987, BTB/POZ domain-containing protein 12

SwissProt ID

Q8IY92 (Human)

Gene ID

84464 (SLX4)

Available reactivities

Hu (Human), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of BTBD12 antibody

This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kise PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of D lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BTBD12 antibody

  Rabbit Polyclonal Anti-SLX4 Antibody  
BTBD12 Rabbit IgG Purified Hu, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

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