BUB1A antibody

Principal name

BUB1A antibody

Alternative names for BUB1A antibody

BUB1L, Mitotic checkpoint serine/threonine-protein kinase BUB1

SwissProt ID

O08901 (Mouse), O43683 (Human)

Gene ID

699 (BUB1), 12235 (Bub1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of BUB1A antibody

The Mitotic Checkpoint Complex (MCC), which contains Bub1, Bub1b, Bub3, Mad2, and Cdc20, controls chromosome segregation and monitors kinetochore-microtubule interactions. During mitosis, the MCC complex inhibits the ubiquitin ligase activity of the Aphase Promoting Complex/Cyclosome (APC/C), thereby preventing cells with uligned chromosomes from prematurely entering aphase. Research studies have shown that Bub1b and Bub1 kises are mutated in several types of human maligncies including hematopoietic, colorectal, lung, and breast cancers. Biallelic mutations in Bub1b have been found in mosaic variegated aneuploidy syndrome and premature chromatid separation syndrome. Bub1b mouse germline knockouts are embryonic lethal with heterozygous animals displaying genetic instability, early aging phenotypes, and increased cancer susceptibility. Bub3 binds both Bub1 and Bub1b, facilitating their recruitment to kinetochores, and is required for functiol microtubule-kinetochore interactions.

Items 1 to 20 of 21 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

BUB1A (N-term) antibody

  Rabbit Polyclonal Bub1 Antibody  
Western blot analysis of bub1 in A-20 lysate with bub1 antibody at (A) 2 and (B) 4 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BUB1A antibody

  Rabbit polyclonal anti-BUB1 antibody  
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using BUB1 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

BUB1A antibody

  Rabbit polyclonal anti-BUB1 antibody  
Western blot analysis of extracts from COLO205 cells, using BUB1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

BUB1A antibody

  Rabbit anti-BUB1 Polyclonal Antibody  
Western blot analysis of extracts of HeLa cell line , using BUB1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BUB1A antibody

  Rabbit Polyclonal Anti-BUB1 Antibody  
Western blot analysis of BUB1 expression in COLO205 cells Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

BUB1A antibody

  Rabbit Polyclonal Anti-BUB1 Antibody  
BUB1A Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

BUB1A antibody

Small intestine: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms P, WB
50 µg / €470.00
  Acris Antibodies GmbH

BUB1A (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

BUB1A antibody

BUB1A Mouse IgG1 14H5 Purified Hu ICC/IF, IP, WB
50 µg / €380.00
  Acris Antibodies GmbH

BUB1A antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using BUB1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
50 µg / €230.00
  Assay Biotech

BUB1A antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using BUB1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

BUB1 - human gene knockout kit via CRISPR

BUB1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

BUB1 - human gene knockout kit via CRISPR

BUB1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

BUB1A

  Recombinant protein of human budding uninhibited by benzimidazoles 1 homolog (yeast) (BUB1)  
BUB1A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

BUB1 overexpression lysate

BUB1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, BUB1 (mGFP-tagged) - Human budding uninhibited by benzimidazoles 1 homolog (yeast) (BUB1), 200 uL, >10^7 TU/mL

Lenti ORF particles, BUB1 (mGFP-tagged) - Human budding uninhibited by benzimidazoles 1 homolog (yeast) (BUB1), 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, BUB1 (Myc-DDK tagged) - Human budding uninhibited by benzimidazoles 1 homolog (yeast) (BUB1) , 200 uL, >10^7 TU/mL

Lenti ORF particles, BUB1 (Myc-DDK tagged) - Human budding uninhibited by benzimidazoles 1 homolog (yeast) (BUB1) , 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Bub1 (GFP-tagged) - Mouse budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Bub1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Bub1 (GFP-tagged) - Mouse budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Bub1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,850.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bub1 (GFP-tagged) - Mouse budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Bub1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Bub1 (GFP-tagged) - Mouse budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Bub1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,850.00
  OriGene Technologies, Inc.

Lenti ORF particles, Bub1 (Myc-DDK-tagged) - Mouse budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Bub1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Bub1 (Myc-DDK-tagged) - Mouse budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Bub1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,670.00
  OriGene Technologies, Inc.

Items 1 to 20 of 21 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn