Alternative names for C11orf51 antibody
HSPC020, Uncharacterized protein C11orf51
Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)
Background of C11orf51 antibody
APC15 is a component of the aphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.