C12orf40 antibody

Principal name

C12orf40 antibody

Alternative names for C12orf40 antibody

Uncharacterized protein C12orf40

SwissProt ID

Q86WS4 (Human)

Gene ID

283461 (C12orf40)

Available reactivities

Hu (Human), Rt (Rat), Eq (Equine), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of C12orf40 antibody

Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf40 gene product has been provisionally designated C12orf40 pending further characterization.

General readings

Ota,T., (2004) Nat. Genet. 36 (1), 40-45

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

C12orf40 antibody

  Rabbit Polyclonal Anti-C12orf40 Antibody  
WB Suggested Anti-C12orf40 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human heart Rabbit IgG Purified Eq, Hu, Por WB
50 µg / €325.00
  OriGene Technologies, Inc.

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