C16orf57 antibody

Principal name

C16orf57 antibody

Alternative names for C16orf57 antibody

UPF0406 protein C16orf57, FLJ13154

SwissProt ID

Q0II50 (Bovin), Q5I0I5 (Rat), Q7ZYI9 (Xenla), Q91W78 (Mouse), Q9BQ65 (Human)

Gene ID

79650 (C16orf57)

Available reactivities

Hu (Human), Por (Porcine), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Goat, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of C16orf57 antibody

Involvement in disease;Defects in C16orf57 are the cause of poikiloderma with neutropenia (PN). PN is a genodermatosis characterized by poikiloderma, pachyonychia and chronic neutropenia. The disorder starts as a papular erythematous rash on the limbs during the first year of life. It gradually spreads centripetally and, as the papular rash resolves, hypo- and hyperpigmentation result, with development of telangiectasias. Another skin manifestation is pachyonychia, but alopecia and leukoplakia are distinctively absent. One of the most important extracutaneous symptoms is an increased susceptibility to infections, mainly affecting the respiratory system, primarily due to a chronic neutropenia and to neutrophil functional defects. Bone marrow abnormalities account for neutropenia and may evolve into myelodysplasia associated with the risk of leukemic transformation. Poikiloderma with neutropenia shows phenotypic overlap with Rothmund-Thomson syndrome.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

C16orf57 (154-167) antibody

(0.3ug/ml) staining of Human Skin lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Por E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

C16orf57 antibody

Western Blot analysis of C16orf57 expression in transfected 293T cell line (H00079650-T01) by C16orf57 MaxPab polyclonal antibody.

Lane 1: FLJ13154 transfected lysate(29.26 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

C16orf57 antibody

Western Blot analysis of C16orf57 expression in transfected 293T cell line (H00079650-T01) by C16orf57 MaxPab polyclonal antibody.

Lane 1: FLJ13154 transfected lysate(29.26 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

C16orf57 antibody

Immunohistochemistry-Paraffin: C16orf57 Antibody [NBP1-82268] Immunohistochemical staining of human colon shows moderate luminal membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

C16orf57

C16orf57 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

FLJ13154 293T Cell Transient Overexpression Lysate(Denatured)

FLJ13154 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

USB1 overexpression lysate

USB1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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