C17orf42 antibody

Principal name

C17orf42 antibody

Alternative names for C17orf42 antibody

UPF0629 protein C17orf42

SwissProt ID

A6QPR9 (Bovin), Q4KM51 (Rat), Q5SSK3 (Mouse), Q96QE5 (Human)

Gene ID

79736 (TEFM)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Por (Porcine)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of C17orf42 antibody

C17orf42 is a 360 amino acid protein that exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

C17orf42 antibody

Host: Rabbit; Target Name: TEFM; Sample Tissue: THP-1 Whole Cell lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

C17orf42 antibody

Host: Rabbit; Target Name: TEFM; Sample Tissue: Fetal Brain lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Can, Hu, Por WB
50 µg / €325.00
  OriGene Technologies, Inc.

C17orf42 antibody

Immunohistochemistry-Paraffin: C17orf42 Antibody [NBP1-82109] Immunohistochemical staining of human lymph node shows moderate cytoplasmic positivity in reaction center cells and cells outside reaction centra. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

C17orf42

C17orf42 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

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