C17orf53 antibody

Principal name

C17orf53 antibody

SwissProt ID

Q8N3J3 (Human)

Gene ID

78995 (C17orf53)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Rb (Rabbit), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of C17orf53 antibody

C17orf53 is a 647 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

C17orf53 antibody

Host: Rabbit; Target Name: C17orf53; Sample Tissue: OVCAR-3 Whole Cell lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Bov, Can, Eq, Hu, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

C17orf53 antibody

Host: Rabbit; Target Name: C17orf53; Sample Tissue: MCF7 Whole Cell lysates; Antibody Dilution: 1.0ug/ml Rabbit IgG Purified Bov, Can, Eq, Hu, Por WB
50 µg / €325.00
  OriGene Technologies, Inc.

C17orf53 antibody

C17orf53 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

C17orf53 antibody

Immunohistochemistry-Paraffin: C17orf53 Antibody [NBP1-93493] Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in purkinje cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

C17orf53 antibody

Immunohistochemistry-Paraffin: C17orf53 Antibody [NBP1-93494] - Immunohistochemical staining of human lung shows strong cytoplasmic positivity in macrophages. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

C17orf53 antibody

Immunohistochemistry-Paraffin: C17orf53 Antibody [NBP1-93495] Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

C17orf53

C17orf53 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

C17orf53 overexpression lysate

C17orf53 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

8 Item(s)

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