C17orf59 antibody

Principal name

C17orf59 antibody

Gene ID

54785 (C17orf59)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), Gt (Goat)

Available hosts


Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of C17orf59 antibody

C17orf59 is a 357 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

General readings

Kimura, K., et al. Genome Res. 16(1):55-65(2006) Suzuki, Y., et al. Gene 200 (1-2), 149-156 (1997)

3 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

C17orf59 antibody

C17orf59 Rabbit IgG Purified Eq, Gt, Hu, Rt WB
  OriGene Technologies, Inc.

C17orf59 (Center) antibody

C17orf59 Rabbit Ig Aff - Purified Hu, Ms WB
  Acris Antibodies GmbH

C17orf59 antibody

C17orf59 Rabbit IgG Aff - Purified Hu P
  Novus Biologicals Inc.

3 Item(s)

per page
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