C17orf74 antibody

Principal name

C17orf74 antibody

Alternative names for C17orf74 antibody

Uncharacterized protein C17orf74

SwissProt ID

Q0P670 (Human), Q68FV4 (Rat), Q8C5U4 (Mouse)

Gene ID

201243 (C17orf74)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of C17orf74 antibody

C17orf74 is a 501 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

General readings

Strausberg,R.L., (2002) Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

C17orf74 antibody

WB Suggested Anti-C17orf74 Antibody Titration: 0.2-1 ug/ml; Positive Control: Hela cell lysate Rabbit IgG Purified Eq, Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

C17orf74 antibody

Human HeLa; WB Suggested Anti-C17orf74 Antibody Titration: 0.2-1 ug/ml. Positive Control: Hela cell lysate; C17orf74 antibody - middle region (ARP53323_P050) in Human HeLa cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

C17orf74 antibody

Immunohistochemistry-Paraffin: C17orf74 Antibody [NBP1-91065] Immunohistochemical staining of human fallopian tube shows strong cytoplasmic and membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

C17orf74 overexpression lysate

C17orf74 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

4 Item(s)

per page
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