C17orf77 antibody

Principal name

C17orf77 antibody

Gene ID

146723 (C17orf77)

Available reactivities

Hu (Human)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of C17orf77 antibody

C17orf77 is a 243 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

C17orf77 antibody

Host: Rabbit; Target Name: C17orf77; Sample Tissue: RPMI-8226 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml. Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

C17orf77 antibody

C17orf77 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

C17orf77 antibody

Immunohistochemistry-Paraffin: C17orf77 Antibody [NBP1-93881] Immunohistochemical staining of human heart muscle shows strong cytoplasmic and membranous positivity. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

C17orf77 overexpression lysate

C17orf77 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

4 Item(s)

per page
  • LinkedIn