C1q B subunit antibody

Principal name

C1q B subunit antibody

Alternative names for C1q B subunit antibody

Complement C1qB, Complement 1qB, Complement C1q subcomponent subunit B

SwissProt ID

P02746 (Human), P14106 (Mouse), P31721 (Rat), Q2KIV9 (Bovin)

Gene ID

713 (C1QB), 12260 (C1qb), 29687

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Bov (Bovine), Por (Porcine), Rb (Rabbit), Rt (Rat), GP (Guinea Pig), Eq (Equine)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), EPair for Elisa (EPair), Enzyme Immunoassay (E), Flow Cytometry (F)

Background of C1q B subunit antibody

C1q, a subcomponent of the classical complement pathway, mediates its activation and thereby plays an important role in immune response. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, and anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. However, its ability to modulate the interaction of platelets with collagen and immune complexes suggests C1q influences homeostasis as well as other immune activities, and perhaps thrombotic complications resulting from immune injury. C1qR, also designated C1qR(p) and CD93, is a type I cell surface glycoprotein that mediates the enhancement of phagocytic activity. C1qR binds to ligands with collagen-like regions that contain the consensus motif GE(K/Q/R)GEP to elicit the removal or destruction of pathogens and immune complexes by phagocytosis. Such ligands include the complement protein C1q, mannose-binding lectin (MBL), and pulmonary surfactant protein A (SPA). The C1qR protein contains a C-type carbohydrate recognition domain, five EGF-like domains, a transmembrane domain, and a short cytoplasmic tail, and is detected at 126 kDa under reducing conditions. C1qR is expressed in cells of myeloid lineage, endothelial cells, and platelets. C1qR is also considered a positive marker of all bone marrow repopulating stem cells because it is expressed on both CD34- and CD34+ stem cells from umbilical cord blood and adult bone marrow. In addition to its role in phagocytosis, C1qR may be involved in cellular adhesion.

General readings

Roumenina,L.T., (2006) Biochemistry 45 (13), 4093-4104

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

C1q B subunit antibody

  Rabbit polyclonal anti-C1QB antibody  
Western blot analysis of extracts from Jurkat cells, using C1QB antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

C1q B subunit antibody

  Rabbit polyclonal C1QB Antibody (N-term)  
C1QB Antibody (N-term) (Cat.# TA325080) western blot analysis in human blood plasma tissue lysates (35ug/lane).This demonstrates the C1QB antibody detected the C1QB protein (arrow). Rabbit IgG Purified Hu F, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

C1q B subunit antibody

  Rabbit Polyclonal Anti-C1QB Antibody  
WB Suggested Anti-C1QB Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Stomach Rabbit IgG Purified Bov, Can, GP, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

C1q B subunit antibody

  Rabbit Polyclonal Anti-C1QB Antibody  
WB Suggested Anti-C1QB Antibody Titration: 0.5 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Can, Eq, Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

C1q B subunit antibody

Western blot (WB) analysis of C1q-B antibody (Cat.-No.: AP01469PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

C1q B subunit antibody

Immunofluorescence analysis of A549 cells, using C1QB Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

C1q B subunit antibody

Immunofluorescence analysis of A549 cells, using C1QB Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

C1QB - human gene knockout kit via CRISPR

C1QB - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

C1QB - human gene knockout kit via CRISPR

C1QB - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

C1QB - human gene knockout kit via CRISPR

C1QB - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

C1QB - human gene knockout kit via CRISPR

C1QB - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

C1qb - mouse gene knockout kit via CRISPR

C1qb - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

C1q B subunit

  Recombinant protein of human complement component 1, q subcomponent, B chain (C1QB)  
C1q B subunit Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, C1QB (mGFP-tagged) - Human complement component 1, q subcomponent, B chain (C1QB), 200 uL, >10^7 TU/mL

Lenti ORF particles, C1QB (mGFP-tagged) - Human complement component 1, q subcomponent, B chain (C1QB), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, C1QB (Myc-DDK tagged) - Human complement component 1, q subcomponent, B chain (C1QB) , 200 uL, >10^7 TU/mL

Lenti ORF particles, C1QB (Myc-DDK tagged) - Human complement component 1, q subcomponent, B chain (C1QB) , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, C1qb (GFP-tagged) - Mouse complement component 1, q subcomponent, beta polypeptide (C1qb), 200 uL, >10^7 TU/mL

Lenti ORF particles, C1qb (GFP-tagged) - Mouse complement component 1, q subcomponent, beta polypeptide (C1qb), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, C1qb (Myc-DDK-tagged) - Mouse complement component 1, q subcomponent, beta polypeptide (C1qb), 200 uL, >10^7 TU/mL

Lenti ORF particles, C1qb (Myc-DDK-tagged) - Mouse complement component 1, q subcomponent, beta polypeptide (C1qb), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, C1qb (GFP-tagged ORF) - Rat complement component 1, q subcomponent, beta polypeptide (C1qb), 200 uL, >10^7 TU/mL

Lenti ORF particles, C1qb (GFP-tagged ORF) - Rat complement component 1, q subcomponent, beta polypeptide (C1qb), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, C1qb (Myc-DDK-tagged ORF) - Rat complement component 1, q subcomponent, beta polypeptide (C1qb), 200 uL, >10^7 TU/mL

Lenti ORF particles, C1qb (Myc-DDK-tagged ORF) - Rat complement component 1, q subcomponent, beta polypeptide (C1qb), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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