C1s antibody

Principal name

C1s antibody

Alternative names for C1s antibody

C1 esterase, Complement C1s, Complement 1s, Complement C1s subcomponent, Complement component 1 subcomponent s

SwissProt ID

P09871 (Human), Q0VCX1 (Bovin), Q69DK8 (Pig), Q6P6T1 (Rat)

Gene ID

716 (C1S)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Mky (Monkey)

Available hosts

Mouse, Rabbit, Goat

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E), Immunodiffusion (ID), Immunoprecipitation (IP), Frozen Sections (C), Flow Cytometry (F), Functional assay (FN)

Background of C1s antibody

The complement component proteins, C1, C3, C4, and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation, and cellular chemotaxis. C1q, together with proenzymes C1r and C1s, yield C1, the first component of the classical pathway of the serum complement system. C1 consists of a calcium dependent trimolecular complex of C1r, C1s and C1q in a 2:2:1 ratio. Activated C1s is in the form of a disulfide-linked heterodimer consisting of a heavy chain and a light chain. Defects in the gene encoding for C1s can cause selective C1s deficiency, a disorder characterized by early onset of various autoimmune diseases.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

C1s antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504082) Mouse IgG2a OTI4E3 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

C1s antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504245) Mouse IgG2a OTI5F2 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

C1s antibody

Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504246) Mouse IgG2a OTI2D11 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

C1s antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA504247) Mouse IgG2a OTI2A8 Purified Hu, Mky, Ms, Rt P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

C1s antibody

Western blot analysis of extracts from Jurkat cells and COLO cells, using C1S antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

C1s antibody

Western blot analysis of extracts from 293 cells treated with etoposide (25uM, 1hour) and HeLa cells treated with etoposide (25uM, 24hours), using C1S (heavy chain, Cleaved-Arg437) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

C1s antibody

Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-C1S mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503953) Mouse IgG1 OTI1G1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

C1s antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C1S (RC218963, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C1S. Mouse IgG1 OTI4D10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

C1s antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C1S (RC218963, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C1S. Mouse IgG1 OTI4D9 Purified Can, Hu, Mky, Ms, Rt F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

C1s antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C1S (RC218963, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C1S. Mouse IgG1 OTI3B11 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

C1s antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY C1S (RC218963, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-C1S. Mouse IgG1 OTI2F5 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

C1s antibody

C1s Mouse IgG1 M81 Purified Hu C, E, FN, IP, P, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

C1s (activated) antibody

C1s Mouse IgG2a M241 Purified Hu C, E, FN, IP, P, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

C1s antibody

Western blot (WB) analysis of C1s antibody (Cat.-No.: AP21153PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

C1s antibody

C1s Goat Serum Hu ID, IP
1 ml / €250.00
  Acris Antibodies GmbH

C1s antibody

Human Placenta (formalin-fixed, paraffin-embedded) stained with C1S antibody AP22474PU-N at 5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat IgG Purified Hu E, P
50 µg / €470.00
  Acris Antibodies GmbH

C1s antibody

C1S MaxPab polyclonal antibody. Western Blot analysis of C1S expression in human liver. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

C1s antibody

C1s Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

C1s antibody

C1S MaxPab rabbit polyclonal antibody. Western Blot analysis of C1S expression in human kidney. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

C1s antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using C1S Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, P, WB
50 µg / €205.00
  Assay Biotech

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