C9orf116 antibody

Principal name

C9orf116 antibody

Alternative names for C9orf116 antibody

Pierce1, UPF0691 protein C9orf116, p53-induced expression in RB-null cells protein 1

Gene ID

138162 (C9orf116)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), GP (Guinea Pig), Por (Porcine), Rt (Rat), Ze (Zebrafish)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of C9orf116 antibody

PIERCE1, also known as C9orf116, is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation (1,2). PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer (3-4). PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies (1-3).

General readings

Sung YH, Kim HJ, Devkota S, et al. Pierce1, a novel p53 target gene contributing to the ultraviolet-induced DNA damage response. Cancer Res. 2010; 70:10454-63.

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

C9orf116 (N-term) antibody

Western blot analysis of PIERCE1 in A20 cell lysate with PIERCE1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

C9orf116 antibody

Host: Rabbit; Target Name: C9orf116; Sample Tissue: Placenta lysates; Antibody Dilution: 1.0 ug/ml. Rabbit IgG Purified Bov, GP, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

C9orf116 (N-term) Control Peptide

Western blot analysis in A20 cell lysate with PIERCE1 antibody Cat.-No AP55622PU-N at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
50 µg / €160.00
  Acris Antibodies GmbH

C9orf116 antibody

Immunohistochemistry-Paraffin: C9orf116 Antibody [NBP1-81136] Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

C9orf116 overexpression lysate

C9orf116 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

5 Item(s)

per page
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