CABLES1 antibody

Principal name

CABLES1 antibody

Alternative names for CABLES1 antibody

Ik3-1, CDK5 and ABL1 enzyme substrate 1, Interactor with CDK3 1

SwissProt ID

Q8TDN4 (Human), Q9ESJ1 (Mouse)

Gene ID

91768 (CABLES1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Enzyme Immunoassay (E)

Background of CABLES1 antibody

Normal Abl function is essential for humans because Philadelphia chromosome translocation involving the ABL gene causes chronic myelogenous leukemia. Abl associates with a broad range of targets and appears to function in various signaling pathways. Cables, a 568 amino-acid protein, links Abl to cyclin-dependent kinase 5 (Cdk5). Cables bound to Cdk5 functions as a substrate for phosphorylation by the Cdk5/p35 kinase. Cables contains an area of weak homology to cyclin A and cyclin C. In addition to its C-terminal Cdk5 binding domain, Cables also has six potential SH3 binding motifs (PXXP) clustered around the amino terminus, two of which are similar to motifs known to bind the Abl SH3 domain. Cables forms a trimolecular complex with Cdk5 and Abl in vivo. All three proteins colocalize within cortical axons, particularly in their growth cones. Cables and Abl may function as adaptor or scaffolding proteins to bind to Cdk5 and control its subcellular location in the neuron.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CABLES1 antibody

Western blot analysis of extracts from LOVO cells, using Ik3-1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CABLES1 antibody

WB Suggested Anti-CABLES1 Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CABLES1 antibody

Western blot (WB) analysis of Cables1 antibody (Cat-No.: AP06793PU-N) at 1/500 dilution Lane1:DLD whole cell lysate Lane2:Mouse kidney tissue lysate Lane3:Rat kidney tissue lysate Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CABLES1 antibody

Immunofluorescence of purified MaxPab antibody to CABLES1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

CABLES1 antibody

Western blot analysis of extracts from LOVO cells, using Ik3-1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €205.00
  Assay Biotech

CABLES1 antibody

Western blot analysis of extracts from LOVO cells, using Ik3-1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €310.00
  Assay Biotech

CABLES1 antibody

Immunohistochemical analysis of CABLES1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CABLES1 antibody

Immunohistochemical analysis of CABLES1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CABLES1 antibody

Immunohistochemical analysis of CABLES1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CABLES1 antibody

Western Blot: Cables1 Antibody [NB100-92443] - Western blot (WB) analysis of Cables1 (K588)  antibody in extracts from LOVO cells. Rabbit IgG Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

CABLES1 antibody

CABLES1 Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

CABLES1 antibody

CABLES1 Rabbit IgG Aff - Purified Hu, Ms E, WB
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CABLES1 (full length, N-term HIS tag, transcript variant 1)

CABLES1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

CABLES1

CABLES1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CABLES1

CABLES1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CABLES1 293T Cell Transient Overexpression Lysate(Denatured)

CABLES1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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