CABLES1 antibody

Principal name

CABLES1 antibody

Alternative names for CABLES1 antibody

Ik3-1, CDK5 and ABL1 enzyme substrate 1, Interactor with CDK3 1

SwissProt ID

Q8TDN4 (Human), Q9ESJ1 (Mouse)

Gene ID

91768 (CABLES1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Enzyme Immunoassay (E)

Background of CABLES1 antibody

Normal Abl function is essential for humans because Philadelphia chromosome translocation involving the ABL gene causes chronic myelogenous leukemia. Abl associates with a broad range of targets and appears to function in various signaling pathways. Cables, a 568 amino-acid protein, links Abl to cyclin-dependent kinase 5 (Cdk5). Cables bound to Cdk5 functions as a substrate for phosphorylation by the Cdk5/p35 kinase. Cables contains an area of weak homology to cyclin A and cyclin C. In addition to its C-terminal Cdk5 binding domain, Cables also has six potential SH3 binding motifs (PXXP) clustered around the amino terminus, two of which are similar to motifs known to bind the Abl SH3 domain. Cables forms a trimolecular complexwith Cdk5 and Abl in vivo. All three proteins colocalize within cortical axons, particularly in their growth cones. Cables and Abl may function as adaptor or scaffolding proteins to bind to Cdk5 and control its subcellular location in the neuron.

10 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CABLES1 antibody

  Rabbit polyclonal anti-CABLES1 (Ik3-1) antibody  
Western blot analysis of extracts from LOVO cells, using Ik3-1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CABLES1 antibody

  Rabbit Polyclonal Anti-CABLES1 Antibody  
WB Suggested Anti-CABLES1 Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Heart Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CABLES1 antibody

  Rabbit Polyclonal Anti-CABLES1 Antibody  
CABLES1 Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CABLES1 antibody

Western blot (WB) analysis of Cables1 antibody (Cat-No.: AP06793PU-N) at 1/500 dilution Lane1:DLD whole cell lysate Lane2:Mouse kidney tissue lysate Lane3:Rat kidney tissue lysate Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CABLES1 antibody

Western blot analysis of extracts from LOVO cells, using Ik3-1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €230.00
  Assay Biotech

CABLES1 antibody

Western blot analysis of extracts from LOVO cells, using Ik3-1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €330.00
  Assay Biotech

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CABLES1 (full length, N-term HIS tag, transcript variant 1)

  Purified recombinant protein of Human Cdk5 and Abl enzyme substrate 1 (CABLES1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug  
CABLES1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CABLES1 (mGFP-tagged) - Human Cdk5 and Abl enzyme substrate 1 (CABLES1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CABLES1 (mGFP-tagged) - Human Cdk5 and Abl enzyme substrate 1 (CABLES1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, CABLES1 (Myc-DDK tagged) - Human Cdk5 and Abl enzyme substrate 1 (CABLES1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, CABLES1 (Myc-DDK tagged) - Human Cdk5 and Abl enzyme substrate 1 (CABLES1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, CABLES1 (Myc-DDK tagged) - Human Cdk5 and Abl enzyme substrate 1 (CABLES1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, CABLES1 (Myc-DDK tagged) - Human Cdk5 and Abl enzyme substrate 1 (CABLES1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,160.00
  OriGene Technologies, Inc.

10 Item(s)

per page
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