CACNA1A antibody

Principal name

CACNA1A antibody

Alternative names for CACNA1A antibody

Cav2.1, Brain calcium channel I, CACH4, CACN3, CACNL1A4, Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-gated calcium channel subunit alpha, Calcium channel L type alpha-1 polypeptide isoform 4

SwissProt ID

O00555 (Human), O73705 (Chick), P54282 (Rat), P97445 (Mouse)

Gene ID

25398 (Cacna1a), 773 (CACNA1A), 12286

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of CACNA1A antibody

Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits polymorphic variation due to (CAG)n-repeats. Multiple transcript variants encoding different isoforms have been found for this gene. In one set of transcript variants, the (CAG)n-repeats occur in the 3' UTR, and are not associated with any disease. But in another set of variants, an insertion extends the coding region to include the (CAG)n-repeats which encode a polyglutamine tract. Expansion of the (CAG)n-repeats from the normal 4-16 to 21-28 in the coding region is associated with spinocerebellar ataxia 6.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CACNA1A antibody

Western blot analysis of rat brain membranes: 1. Anti-CaV2.1antibody, (1:200). 2. Anti-CaV2.1 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CACNA1A antibody

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (CACNA1A Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CACNA1A antibody

Western blot analysis alpha1A antibody on rat brain lysate. Rabbit IgG Purified Rt WB
0.1 mg / €370.00
  Acris Antibodies GmbH

CACNA1A antibody

CACNA1A Rabbit IgG Aff - Purified Rt WB
0.1 mg / €430.00
  Acris Antibodies GmbH

CACNA1A antibody

CACNA1A Rabbit Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CACNA1A (Myc-DDK tagged) - Human calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (CACNA1A), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CACNA1A (Myc-DDK tagged) - Human calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (CACNA1A), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

6 Item(s)

per page
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