CACNA1A antibody

Principal name

CACNA1A antibody

Alternative names for CACNA1A antibody

Cav2.1, Brain calcium channel I, CACH4, CACN3, CACNL1A4, Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-gated calcium channel subunit alpha, Calcium channel L type alpha-1 polypeptide isoform 4

SwissProt ID

O00555 (Human), O73705 (Chick), P54282 (Rat), P97445 (Mouse)

Gene ID

25398 (Cacna1a), 773 (CACNA1A)

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P)

Background of CACNA1A antibody

Voltage-sensitive calcium channels (VSCCs) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1a gives rise to p and/or q-type calcium currents. P/q-type calcium channels belong to the 'high-voltage activated' (hva) group and are blocked by the funnel toxin (ftx) and by the omega-agatoxin-IVA (omega-aga-IVA). They are however insensitive to dihydropyridines (dhp), and omega- conotoxin-GVIA (omega-ctx-GVIA). voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CACNA1A antibody

Western blot analysis of rat brain membranes: 1. Anti-CaV2.1antibody, (1:200). 2. Anti-CaV2.1 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CACNA1A antibody

Western blot analysis alpha1A antibody on rat brain lysate. Rabbit IgG Purified Rt WB
0.1 mg / €360.00
  Acris Antibodies GmbH

CACNA1A antibody

CACNA1A Rabbit IgG Aff - Purified Rt WB
10 Blots / €420.00
  Acris Antibodies GmbH

CACNA1A antibody

CACNA1A Rabbit Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CACNA1A antibody

CACNA1A Rabbit Serum Hu C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

5 Item(s)

per page
  • LinkedIn