CACNA1E antibody

Principal name

CACNA1E antibody

Alternative names for CACNA1E antibody

CACH6, CACNL1A6, Cav2.3, Brain calcium channel II, Voltage-dependent R-type calcium channel subunit alpha-1E, Voltage-gated calcium channel subunit alpha

SwissProt ID

Q07652 (Rat), Q15878 (Human), Q61290 (Mouse)

Gene ID

777 (CACNA1E), 54234

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P), Flow Cytometry (F)

Background of CACNA1E antibody

Voltage-dependent Ca2+ channels (Cav channels) are pivotal players in many physiological roles such as secretion, contraction, migration and excitation.The voltage dependent Ca2+ channels are composed of several subunits; a1, Ã?, a2d and ?. Cav channels were origilly divided into six physiological types: L, N , P, Q, R, and T type.The Cav2.3 (formerly med a1E) protein, forms the R type channels. R-type channels are highly sensitive to both SNX-482 (#RTS-500) and NiCl2. Cav2.3 channels were shown to mediate fast excitatory transmission in several sypses including the hippocampus.Cav2.3 channels can be modulated by the muscarinic G-protein coupled receptors. In HEK-293 cells, expressing Cav2.3 channels, the R-type channel was shown to be both facilitated and inhibited by m1 and m2 muscarinic receptors. However, inhibition was much weaker than facilitation for the m1 receptor, while for m2 receptors, inhibition was much more pronounced than activation.Facilitation and inhibition by the same receptors was probably exerted via different pathways as was indicated by their response to various inhibitors.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CACNA1E antibody

Western blot analysis of rat brain membranes: 1. Anti-CaV2.3 antibody, (1:200). 2. Anti-CaV2.3 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CACNA1E antibody

CACNA1E Rabbit IgG Purified Hu, Rt WB
0.1 mg / €360.00
  Acris Antibodies GmbH

CACNA1E antibody

CACNA1E Rabbit Hu, Ms, Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CACNA1E antibody

Western blot analysis of Cav2.3 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rb, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CACNA1E antibody

Western blot analysis of Cav2.3 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rb, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CACNA1E antibody

Western blot analysis of Cav2.3 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rb, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CACNA1E antibody

CACNA1E Rabbit Serum Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CACNA1E

CACNA1E Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CACNA1E

CACNA1E Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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