CACNA1H antibody

Principal name

CACNA1H antibody

Alternative names for CACNA1H antibody

Cav3.2, Voltage-dependent T-type calcium channel subunit alpha-1H, Voltage-gated calcium channel subunit alpha Cav3.2, Low-voltage-activated calcium channel alpha1 3.2 subunit

SwissProt ID

O88427 (Mouse), O95180 (Human), Q9EQ60 (Rat)

Gene ID

8912 (CACNA1H), 114862 (Cacna1h)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of CACNA1H antibody

Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces.
There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics.
The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels; each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inward-rectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2).
Specifically, Cav3.2 is a protein which in humans is encoded by the CACNA1H gene. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (3, 4). Studies also suggest that the up-regulations of Cav3.2 may participate in the progression of prostate cancer toward an androgen-independent stage (5).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CACNA1H antibody

Western blot analysis of rat DRG lysates: 1. Anti-Cav3.2 antibody, (1:200). 2. Anti-Cav3.2 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CACNA1H antibody

IHC analysis of Cav3.2 in frozen sections of mouse brain extract using TA309309. Mouse IgG1 S55-10 Purified Hu ICC/IF, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CACNA1H antibody

Western blot analysis of extracts from A549 cells, using CACNA1H antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CACNA1H antibody

Western blot analysis of CACNA1H in 293 cell lysate with CACNA1H antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CACNA1H antibody

Stable cell immunoblot: extracts of HEK cells stably-expressing Flag-tagged Cav3.2, Cav3.1 or untagged Kv2.1 plasmid and probed with N55/10 TC supe (left) or Rabbit anti-Flag (right). Mouse IgG1 N55/10 Supernatant Hu, Ms C, ICC/IF, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

CACNA1H antibody

Stable cell immunoblot: extracts of HEK cells stably-expressing Flag-tagged Cav3.2, Cav3.1 or untagged Kv2.1 plasmid and probed with N55/10 TC supe (left) or Rabbit anti-Flag (right). Mouse IgG1 N55/10 Purified Hu, Ms C, ICC/IF, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

CACNA1H antibody

Western blot (WB) analysis of T-type Ca++ CP α1H antibody (Cat.-No AP01505PU-N) in extracts from A549 cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CACNA1H (alpha-1) antibody

CACNA1H Rabbit Purified Hu, Ms, Rt C, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

CACNA1H antibody

Western blot analysis of extracts from A549 cells, using CACNA1H Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

CACNA1H antibody

Western blot analysis of extracts from A549 cells, using CACNA1H Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

CACNA1H antibody

Western Blot: T-type Ca++ CP alpha1H Antibody [NBP1-01047] - Western blot (WB) analysis of T-type Ca++ CP alpha1H (P492) antibody in extracts from A549 cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €420.00
  Novus Biologicals Inc.

CACNA1H antibody

CACNA1H Rabbit Serum Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

CACNA1H antibody

Immunohistochemistry-Paraffin: Cav3.2 Antibody (S55-10) [NBP1-22444] - IHC analysis of Cav3.2 in frozen sections of mouse brain extract using NBP1-22444. Mouse IgG1 S55-10 Purified Hu, Ms, Rt C, ICC/IF, IP, P, WB
0.1 mg / €450.00
  Novus Biologicals Inc.

CACNA1H antibody

CACNA1H Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

CACNA1H antibody

CACNA1H Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
50 µg / €290.00
  Novus Biologicals Inc.

15 Item(s)

per page
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