CACNA1S antibody

Principal name

CACNA1S antibody

Alternative names for CACNA1S antibody

CACH1, CACN1, CACNL1A3, Cav1.1, Voltage-dependent L-type calcium channel subunit alpha-1S, Voltage-gated calcium channel subunit alpha Cav1.1, Calcium channel L type alpha-1 polypeptide isoform 3 skeletal muscle

SwissProt ID

Q02485 (Rat), Q02789 (Mouse), Q13698 (Human)

Gene ID

779 (CACNA1S)

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P)

Background of CACNA1S antibody

Voltage-sensitive calcium channels mediate the entry of calcium into many types of excitable cells and thus play a key role in neurotransmitter release and excitation-contraction (E-C) coupling. The 1,4-dihydropyridines (DHPs) are synthetic organic compounds which can be used to identify the L-type calcium channels that are found in all types of vertebrate muscle, neuronal and neuroendocrine cells. The DHP receptor is part of the L-type calcium channel complex and is thought to be the voltage sensor in E-C coupling.The purified DHP receptor isolated from triads is composed of at least four subunits. The alpha-1 subunit contains the binding site for the DHPs and shows high sequence homology to the voltage gated sodium channel. The alpha-2 subunit is a large glycoprotein associated with the DHP receptor which was first described in skeletal muscle and is also found in high concentrations in other excitable tissues such as cardiac muscle and brain and in low concentrations in most other tissues studied. The other two subunits that co-purify with the DHP receptor are termed beta and gamma.

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CACNA1S antibody

  Rabbit polyclonal antibody to CACNA1S (calcium channel, voltage-dependent, L type, alpha 1S subunit)  
Sample (30 ug of whole cell lysate). A: 293T. 5% SDS PAGE. TA308209 diluted at 1:1000. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CACNA1S (alpha-1) antibody

CACNA1S Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CACNA1S - human gene knockout kit via CRISPR

CACNA1S - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CACNA1S - human gene knockout kit via CRISPR

CACNA1S - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CACNA1S - human gene knockout kit via CRISPR

CACNA1S - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CACNA1S - human gene knockout kit via CRISPR

CACNA1S - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CACNA1S overexpression lysate

CACNA1S overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CACNA1S (Myc-DDK tagged) - Human calcium channel, voltage-dependent, L type, alpha 1S subunit (CACNA1S), 200 uL, >10^7 TU/mL

Lenti ORF particles, CACNA1S (Myc-DDK tagged) - Human calcium channel, voltage-dependent, L type, alpha 1S subunit (CACNA1S), 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

8 Item(s)

per page
  • LinkedIn