CACNA2D1 antibody

Principal name

CACNA2D1 antibody

Alternative names for CACNA2D1 antibody

CACNL2A, CCHL2A, MHS3, Voltage-dependent calcium channel subunit alpha-2/delta-1

SwissProt ID

O08532 (Mouse), P13806 (Rabit), P54289 (Human), P54290 (Rat)

Gene ID

781 (CACNA2D1), 100009105

Available reactivities

Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Flow Cytometry (F)

Background of CACNA2D1 antibody

Voltage-sensitive calcium channels mediate the entry of calcium into many types of excitable cells and thus play a key role in neurotransmitter release and excitation-contraction (E-C) coupling. The 1,4-dihydropyridines (DHPs) are synthetic organic compounds which can be used to identify the L-type calcium channels that are found in all types of vertebrate muscle, neuronal and neuroendocrine cells. The DHP receptor is part of the L-type calcium channel complex and is thought to be the voltage sensor in E-C coupling. The purified DHP receptor isolated from triads is composed of at least four subunits. The alpha-1 subunit contains the binding site for the DHPs and shows high sequence homology to the voltage gated sodium channel. The alpha-2 subunit is a large glycoprotein associated with the DHP receptor which was first described in skeletal muscle and is also found in high concentrations in other excitable tissues such as cardiac muscle and brain and in low concentrations in most other tissues studied. The other two subunits that co-purify with the DHP receptor are termed beta and gamma.

General readings

Hullin R, Matthes J, von Vietinghoff S, Bodi I, Rubio M, D'Souza K, Friedrich Khan I, Rottlander D, Hoppe UC, Mohacsi P, Schmitteckert E, Gilsbach R, Bunemann M, Hein L, Schwartz A, Herzig S. Increased Expression of the Auxiliary beta(2)-subunit of Ventricular L-type Ca Channels Leads to Single-Channel Activity Characteristic of Heart Failure. PLoS ONE. 2007 Mar 14;2:e292. PMID: 17356701

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CACNA2D1 antibody

TA303244 (0.03µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CACNA2D1 antibody

CACNA2D1 Rabbit Purified Hu, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CACNA2D1 antibody

WB Suggested Anti-CACNA2D1 Antibody Titration: 0.12 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CACNA2D1 antibody

Western blot analysis using anti-CACNA2D antibody at 1.0 µg/ml on K562 cell lysate. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €360.00
  Acris Antibodies GmbH

CACNA2D1 (N-term) antibody

Western blot analysis of CACNA2D1 Antibody (N-term) (AP17917PU-N) in mouse brain tissue lysates (35ug/lane). CACNA2D1 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CACNA2D1 (alpha-2) antibody

Nerve stained with CA2D1 antibody Cat.-No AP55391PU-N in Immunohistochemistry on Paraffin Sections Rabbit Purified Hu, Ms, Rt E, P, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

CACNA2D1 antibody

CACNA2D1 polyclonal antibody ( Cat # PAB7294 ) ( 0.03 µg/ml ) staining of human brain ( cerebellum ) lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CACNA2D1 antibody

Human Muscle; WB Suggested Anti-CACNA2D1 Antibody Titration: 0.12ug/ml. ELISA Titer: 1:312500. Positive Control: Human Muscle; CACNA2D1 antibody - middle region (ARP34952_P050) in Human Muscle cells using Western Blot Rabbit Aff - Purified Can, Chk, Hu, Ms, Por, Rb, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CACNA2D1 antibody

Western blot analysis of CACNA2D1 expression in rat brain (A) whole cell lysates. Rabbit Aff - Purified Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CACNA2D1 antibody

Western blot analysis of CACNA2D1 expression in rat brain (A) whole cell lysates. Rabbit Aff - Purified Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CACNA2D1 antibody

Western blot analysis of CACNA2D1 expression in rat brain (A) whole cell lysates. Rabbit Aff - Purified Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CACNA2D1 antibody

Immunohistochemistry: CACNA2D1 Antibody [NB100-60951] -  CACNA2D1 Antibody [NB100-60951] - NB100-60951 (0.03ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

CACNA2D1 antibody

CACNA2D1 Rabbit IgG Hu, Ms P, WB
0.5 mg / €400.00
  Novus Biologicals Inc.

CACNA2D1 antibody

Immunohistochemistry-Paraffin: CACNA2D1 Antibody [NBP1-86682] - Immunohistochemistry-Paraffin: CACNA2D1 Antibody [NBP1-86682] Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

CACNA2D1 overexpression lysate

CACNA2D1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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