CACNA2D4 antibody

Principal name

CACNA2D4 antibody

Alternative names for CACNA2D4 antibody

Voltage-dependent calcium channel subunit alpha-2/delta-4, Voltage-gated calcium channel subunit alpha-2/delta-4

SwissProt ID

Q5RJF7 (Mouse), Q7Z3S7 (Human)

Gene ID

93589 (CACNA2D4), 319734 (Cacna2d4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Bov (Bovine), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of CACNA2D4 antibody

Voltage-gated Ca2+ (CaV) channels are ubiquitously expressed and function as Ca2+ conducting pores in the plasma membrane. Based on their electrophysiological and pharmacological properties, Ca2+ channels have traditiolly been classified into L, T, N, P, Q, and R types. L-type calcium channels are heteromultimers composed of four independently encoded proteins, the pore-forming a1 subunit, which triggers Ca2+ flow across the membrane, and the auxiliary subunits a2d, ?, and Ã?. The Ca2+ channel a2d subunit is a heavily glycosylated protein that is encoded by a single gene and post-translatiolly cleaved to yield a2 and d subunits linked by a disulfide bond with a single transmembrane segment.The a2d subunit regulates many functiol aspects of Ca2+ channels, such as gating, regulating voltage dependent kinetics, and increasing functiol channel density on the plasma membrane. There are four proteins that comprise CaVa2d: CaVa2d1, CaVa2d2, CaVa2d3 and CaVa2d4. CaVa2d4 participates in the regulation of membrane expression of CaV channels. It is predomintly expressed in certain types of endocrine cells. It is also detected in the erythroblasts in the fetal liver, in the cells of the zo reticularis of the adrel gland and in the basophiles of the pituitary. Defects in CaVa2d4 are the cause of retil cone dystrophy 4 (RCD4). RCD4 is characterized by minimal symptoms except for slowly progressive reduction in visual acuity.

9 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CACNA2D4 antibody

Western blot analysis of extracts from 293 cells and 3T3 cells, using CACNA2D4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CACNA2D4 antibody

Western blot analysis of rat DRG (lanes 1 and 3) and PC12 cells (lanes 2 and 4): 1-2. Anti-Cava2d4 (extracellular) antibody, (1:200). 3-4. Anti-Cava2d4 (extracellular) antibody preincubated with the control antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CACNA2D4 antibody

Host: Rabbit; Target Name: CACNA2D4; Sample Tissue: A549 Whole Cell lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CACNA2D4 antibody

WB Suggested Anti-CACNA2D4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CACNA2D4 antibody

CACNA2D4 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

CACNA2D4 (C-term) antibody

CACNA2D4 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CACNA2D4 antibody

CACNA2D4 Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

CACNA2D4 antibody

Immunohistochemistry-Paraffin: CACNA2D4 Antibody [NBP1-85920] - Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

CACNA2D4 overexpression lysate

CACNA2D4 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

9 Item(s)

per page
  • LinkedIn