CACNB1 antibody

Principal name

CACNB1 antibody

Alternative names for CACNB1 antibody

CAB1, CACNLB1, Voltage-dependent L-type calcium channel subunit beta-1, Calcium channel voltage-dependent subunit beta 1

SwissProt ID

P54283 (Rat), Q02641 (Human), Q8R3Z5 (Mouse), Q9MZL7 (Bovin)

Gene ID

782 (CACNB1), 50688 (Cacnb1)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), African clawed frog, Chk (Chicken), Por (Porcine), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of CACNB1 antibody

Voltage-gated Ca2+ (CaV) channels are ubiquitously expressed and function as Ca2+ conducting pores in the plasma membrane1. Based on their electrophysiological and pharmacological properties, CaV channels have traditiolly been classified into L, T, N, P, Q, and R types. L-type Ca2+ channels are heteromultimers composed of four independently encoded proteins, the pore-forming a1 subunit, which triggers Ca2+ flow across the membrane, and the subunits a2d, ?, and Ã?.CaVÃ? subunits play critical roles in membrane trafficking of the channel complex and regulation of voltage-dependent gating. The CaVÃ? subunit binds to the endoplasmic reticulum (ER) retention sigl in the I-II loop of the a1-subunit, which allows channels to traffic to the surface membrane4. Furthermore, CaVÃ? subunits not only allow for membrane trafficking of the channel complex, they also can play a role in determining the subcellular localization of channels on the surface membrane. There are four distinct CaVÃ? subunits CaVÃ?1, CaVÃ?2, CaVÃ?3 and CaVÃ?4.Three splice variants exist for the Ã?1 subunit: Ã?1a, Ã?1b and Ã?1c. Ã?1a is known to be expressed in skeletal muscle and brain, but not in smooth muscle or heart. Ã?1a appears to be important for the functiol expression of the a1 subunit in skeletal muscle. Ã?1b was identified by cloning in rat brain, heart and hippocampus, and differs from Ã?1a by having a deletion of ~50 amino acids at residue 209, and having a 120-residue C-termil elongation. Ã?1c was cloned from human heart and hippocampus and has the same deletion as Ã?1b, but lacks the C-termil extension.

General readings

Hogan,K., et al., (1999) Neurosci. Lett. 277 (2), 111-114

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CACNB1 antibody

WB Suggested Anti-CACNB1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CACNB1 antibody

Hum. Fetal Heart; Host: Rabbit. Target Name: CACNB1. Sample Tissue: Human Fetal Heart. Antibody Dilution: 1.0ug/ml.; CACNB1 antibody - N-terminal region (ARP34953_P050) in Hum. Fetal Heart cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rb, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

CACNB1 antibody

Western blot analysis of rat brain (lanes 1 and 4), mouse brain (lanes 2 and 5) and rat cortex (lane 3 and 6): 1-3. Anti-CaVß1 antibody, (1:800). 4-6. Anti-CaVß1 antibody preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
50 µl / €325.00
  OriGene Technologies, Inc.

CACNB1 antibody

WB Suggested Anti-CACNB1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CACNB1 antibody

WB Suggested Anti-CACNB1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, GP, Hu, Ms, Rb P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

CACNB1 antibody

WB Suggested Anti-CACNB1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: COLO205 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CACNB1 antibody

WB Suggested Anti-CACNB1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, GP, Hu, Ms, Rb, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CACNB1 antibody

immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with N7/18 (left) or N52A/42 (right) TC supe. Mouse IgG2a N7/18 Supernatant Hu, Ms, Rt C, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

CACNB1 antibody

immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with N7/18 (left) or N52A/42 (right) TC supe. Mouse IgG2a N7/18 Purified Hu, Ms, Rt C, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

CACNB1 antibody

CACNB1 Rabbit IgG Purified Hu WB
0.1 mg / €360.00
  Acris Antibodies GmbH

CACNB1 (C-term) antibody

CACNB1 Antibody (C-term) (Cat. #AP50704PU-N) western blot analysis in HepG2 cell line lysates (35µg/lane).This demonstrates the CACNB1 antibody detected the CACNB1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CACNB1 antibody

Western Blot analysis of CACNB1 expression in transfected 293T cell line (H00000782-T01) by CACNB1 MaxPab polyclonal antibody.

Lane1:CACNB1 transfected lysate(65.78 KDa).
Lane2:Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CACNB1 antibody

CACNB1 Rabbit Serum Hu IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

CACNB1 antibody

Western Blot analysis of CACNB1 expression in transfected 293T cell line (H00000782-T01) by CACNB1 MaxPab polyclonal antibody.

Lane 1: CACNB1 transfected lysate(65.70 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CACNB1 antibody

Western blot analysis of CACNB1 over-expressed 293 cell line, cotransfected with CACNB1 Validated Chimera RNAi ( Cat # H00000782-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with CACNB1 monoclonal antibody (M01), clone 1G6 (Cat # H00000782-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. Mouse IgG2a 1G6 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CACNB1 antibody

CACNB1 Rabbit Hu, Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CACNB1 antibody

Human Brain; WB Suggested Anti-CACNB1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human brain; CACNB1 antibody - N-terminal region (ARP34954_P050) in Human Brain cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Hu, Ms, Rb, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

CACNB1 antibody

Human kidney; CACNB1 antibody - middle region (ARP35579_P050) in Human kidney cells using Immunohistochemistry Rabbit Aff - Purified Bov, Hu, Ms, Rb, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

CACNB1 antibody

Hum. Adult Placenta; Host:Rabbit. Target Name:CACNB1. Sample Tissue:Human Adult Placenta. Antibody Dilution: 1.0ug/ml.; CACNB1 antibody - middle region (ARP35580_P050) in Hum. Adult Placenta cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

CACNB1 antibody

Human MCF-7; WB Suggested Anti-CACNB1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: MCF7 cell lysate; CACNB1 antibody - C-terminal region (ARP36744_P050) in Human MCF-7 cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Hu, Ms, Rb, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

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