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CACNB3 antibody

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Principal name

CACNB3 antibody

Alternative names for CACNB3 antibody

CAB3, CACNLB3, Voltage-dependent L-type calcium channel subunit beta-3, Calcium channel voltage-dependent subunit beta 3

SwissProt ID

P54284 (Human), P54285 (Mouse), P54287 (Rat), Q9MZL3 (Bovin)

Gene ID

784 (CACNB3), 25297 (Cacnb3)

Ncbi ID

NP_000716, NP_036960.1, NP_000716.2, 9606, 10116, CAA54056, NM_000725

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), African clawed frog, Chk (Chicken), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E)

Background of CACNB3 antibody

Voltage-sensitive calcium channels (VSCCs) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-ctx-GVIA) and omega-agatoxin-IVA (omega-aga-IVA). The overall conclusion is that deletion of the beta 3 subunit affects at least three distinct types of High voltage activated Ca2+ channel (L,N and P/Q types), but no single type of channel is solely dependent on beta 3.

General readings

Murakami,M., et al., (1996) Eur. J. Biochem. 236 (1), 138-143

ARP34957_T100 - CACNB3
Human Jurkat; WB Suggested Anti-CACNB3 Antibody Titration: 2.5ug/ml. ELISA Titer: 1:62500. Positive Control: Jurkat cell lysate. CACNB3 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells.; CACNB3 antibody - C-terminal region (ARP34957_T100) in Human Jurkat cells using Western Blot
H00000784-B01P - CACNB3
Western Blot analysis of CACNB3 expression in transfected 293T cell line (H00000784-T01) by CACNB3 MaxPab polyclonal antibody.Lane 1: CACNB3 transfected lysate(53.24 KDa).Lane 2: Non-transfected lysate.
H00000784-D01P - CACNB3
Western Blot analysis of CACNB3 expression in transfected 293T cell line (H00000784-T02) by CACNB3 MaxPab polyclonal antibody.Lane 1: CACNB3 transfected lysate(54.50 KDa).Lane 2: Non-transfected lysate.
H00000784-D01P - CACNB3
CACNB3 MaxPab rabbit polyclonal antibody. Western Blot analysis of CACNB3 expression in A-431.
ARP34958_P050 - CACNB3
Human Jurkat; WB Suggested Anti-CACNB3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Jurkat cell lysate. CACNB3 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells.; CACNB3 antibody - N-terminal region (ARP34958_P050) in Human Jurkat cells using Western Blot
AP23106PU-N - CACNB3
Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)
TP307229 - CACNB3
TA330294 - CACNB3
Host: Rabbit; Target Name: CACNB3; Sample Tissue: Hela Whole Cell lysates; Antibody Dilution: 1.0ug/ml
TA338367 - CACNB3
WB Suggested Anti-CACNB3 Antibody Titration: 2.5 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate CACNB3 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
TA338368 - CACNB3
WB Suggested Anti-CACNB3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate CACNB3 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
CPA9255-100ul - CACNB3
Western blot analysis of CACNB3 expression in mouse brain (A); rat brain (B) whole cell lysates.
CPA9255-100ul - CACNB3
Immunohistochemical analysis of CACNB3 staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

4 Item(s)

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CRISPR

Catalog No. Species Donor Vector  

CACNB3 - human gene knockout kit via CRISPR
CACNB3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CACNB3 - human gene knockout kit via CRISPR
CACNB3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CACNB3 - human gene knockout kit via CRISPR
CACNB3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CACNB3 - human gene knockout kit via CRISPR
CACNB3 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

4 Item(s)

per page

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Species (CRISPR)
  1. Human (4)
Donor Vector
  1. GFP-Puro (1)
  2. Luciferase-Puro (1)
  3. RFP-BSD (1)
  4. mBFP-Neo (1)
Manufacturer
  1. Acris - OriGene (4)
Service
  • OriGene EU
  • Acris Antibodies GmbH
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  • D-32052 Herford
  • Germany
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  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
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  • orders: ordering@acris-online.de
 
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