CACNG2 antibody

Principal name

CACNG2 antibody

Alternative names for CACNG2 antibody

TARP gamma-2, Voltage-dependent calcium channel gamma-2 subunit, Neuronal voltage-gated calcium channel gamma-2 subunit, Transmembrane AMPAR regulatory protein gamma-2

SwissProt ID

O88602 (Mouse), Q71RJ2 (Rat), Q9Y698 (Human)

Gene ID

10369 (CACNG2), 12300 (Cacng2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of CACNG2 antibody

Voltage-dependent calcium channels (VDCCs) are large (>400 kDa) heteromers which contain, minimally, three core subunits alpha1, alpha2/delta, beta in a 1:1:1 stoichiometry. Expression of VDCC gene products in Xenopus oocytes, or transfected cells shows that the alpha1 subunits contain the ion channel pore while the auxiliary alpha2/delta and beta subunits confer optimal cell surface expression and channel kinetics1. Until recently, the only exception to the above paradigm was the skeletal muscle VDCC, which, in addition to the alpha1, alpha2/delta, beta core motif, also has an additional tightly associated integral membrane glycoprotein subunit termed gamma 1. Upon co-expression with the alpha1.1, alpha2/delta1, beta1a subunits of the skeletal muscle VDCC, gamma subunits alter the peak currents, and the kinetics of channel activation and inactivation with the overall effect being a normalisation of currents to those resembling the endogenous channel2. Together, these results suggest that gamma subunits modulate skeletal muscle VDCCs by stabilising their conformation. The gamma 2 subunits, or stargazin, the product of a gene mutated in the stargazer mouse, is a homolog of the gamma 1 channel and is selectively expressed in the brain. It is considered to be a putative neuronal Ca2+ channel subtype mainly based on its homology to the gamma 1.

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CACNG2 (C-term) antibody

  Rabbit Anti-Stargazin Antibody  
Western blot of rat synaptic membrane (SPM) showing specific immunolabeling of the ~ 36k stargazin protein. Rabbit IgG Aff - Purified Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CACNG2 (203-323, Cytopl. Dom.) antibody

  Mouse Monoclonal Anti-TARPGamma2/Stargazin Antibody  
WB of rat brain lysate showing detection of ~35 kDa TARP Gamma2/Stargazin protein using Anti-TARP Gamma2/Stargazin antibody.  Lane 1: MW ladder. Lane 2: Anti-TARP Gamma2 (1:100). Lane 3: Anti-TARP Gamma2 (1:250). Lane 4: Anti-TARP Gamma2 (1:500). Lane 5: Anti-TARP Gamma2 (1:1000).  Load: 20 µg RB lysate per lane. Block: 5% milk + TBST 1hr at RT. Primary antibody: Mouse Anti-TARP Gamma2 monoclonal antibody incubated for 60 min at RT. Secondary antibody: Goat Anti-Mouse HRP antibody at 1:50 for 60 min at RT. Colour Development: TMB solution for 30 min at RT. Predicted/Observed size: ~ 35 kDa. Other band(s) (unknown): ~60kDa, ~75kDa. Mouse IgG2a S245-1 Purified Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CACNG2 antibody

  Rabbit Polyclonal Anti-CaVgamma2  
Western blot analysis of rat brain membranes: 1. Anti-Cav?2 antibody, (1:200). 2. Anti-Cav?2 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CACNG2 antibody

Immunoblot versus low-speed pellet samples from wild-type (WT) and Stargazer mutant (STG) mice and probed with N245/1 TC supe. Data courtesy of Susumu Tomita, Yale University. Mouse IgG2a N245/1 Supernatant Ms, Rt ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

CACNG2 antibody

Immunoblot versus low-speed pellet samples from wild-type (WT) and Stargazer mutant (STG) mice and probed with N245/1 TC supe. Data courtesy of Susumu Tomita, Yale University. Mouse IgG2a N245/1 Purified Ms, Rt ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

CACNG2 antibody

Western blot analysis using gamma2 antibody on rat brain lysate. Rabbit IgG Purified Hu WB
0.1 mg / €370.00
  Acris Antibodies GmbH

CACNG2/4/8 (203-323, Cytopl. Dom.) antibody

  Mouse Monoclonal Anti-TARP Gamma2-4-8 (Stargazin) Antibody  
WB of rat brain lysate showing detection of ~35-55 kDa TARP Gamma2-4-8 (Stargazin) protein using Anti-Tarp Gamma2-4-8 antibody.  Lane 1: MW ladder. Lane 2: Anti-TARP Gamma2-4-8 (1:100). Lane 3: Anti-TARP Gamma2-4-8 (1:250). Lane 4: Anti-TARP Gamma2-4-8 (1:500). Lane 5: Anti-TARP Gamma2-4-8 (1:1000).  Load: 20 µg RB lysate per lane. Block: 5% milk + TBST 1hr at RT. Primary antibody: Mouse Anti-TARP Gamma2-4-8 monoclonal antibody incubated for 60 min at RT. Secondary antibody: Goat Anti-Mouse HRP antibody at 1:50 for 60 min at RT. Colour Development: TMB solution for 30 min at RT. Predicted/Observed size: ~ 55 kDa. Other band(s) (faint): ~37kDa, ~40kDa, ~75kDa. Mouse IgG2a S245-36 Purified Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CACNG2/4/8 antibody

Adult rat brain membrane immunoblot Mouse IgG2a N245/36 Supernatant Ms, Rt ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

CACNG2/4/8 antibody

Adult rat brain membrane immunoblot Mouse IgG2a N245/36 Purified Ms, Rt ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

CRISPR

Catalog No. Species Donor Vector  

CACNG2 - human gene knockout kit via CRISPR

CACNG2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CACNG2 - human gene knockout kit via CRISPR

CACNG2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CACNG2 - human gene knockout kit via CRISPR

CACNG2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CACNG2 - human gene knockout kit via CRISPR

CACNG2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cacng2 - mouse gene knockout kit via CRISPR

Cacng2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cacng2 - mouse gene knockout kit via CRISPR

Cacng2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cacng2 - mouse gene knockout kit via CRISPR

Cacng2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cacng2 - mouse gene knockout kit via CRISPR

Cacng2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CACNG2 (mGFP-tagged) - Human calcium channel, voltage-dependent, gamma subunit 2 (CACNG2), 200 uL, >10^7 TU/mL

Lenti ORF particles, CACNG2 (mGFP-tagged) - Human calcium channel, voltage-dependent, gamma subunit 2 (CACNG2), 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, CACNG2 (Myc-DDK tagged) - Human calcium channel, voltage-dependent, gamma subunit 2 (CACNG2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, CACNG2 (Myc-DDK tagged) - Human calcium channel, voltage-dependent, gamma subunit 2 (CACNG2) , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

19 Item(s)

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