CACNG2 antibody

Principal name

CACNG2 antibody

Alternative names for CACNG2 antibody

TARP gamma-2, Voltage-dependent calcium channel gamma-2 subunit, Neuronal voltage-gated calcium channel gamma-2 subunit, Transmembrane AMPAR regulatory protein gamma-2

SwissProt ID

O88602 (Mouse), Q71RJ2 (Rat), Q9Y698 (Human)

Gene ID

10369 (CACNG2), 12300 (Cacng2), 84347

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CACNG2 antibody

Voltage-dependent calcium channels (VDCCs) are large (>400 kDa) heteromers which contain, minimally, three core subunits alpha1, alpha2/delta, beta in a 1:1:1 stoichiometry. Expression of VDCC gene products in Xenopus oocytes, or transfected cells shows that the alpha1 subunits contain the ion channel pore while the auxiliary alpha2/delta and beta subunits confer optimal cell surface expression and channel kinetics1. Until recently, the only exception to the above paradigm was the skeletal muscle VDCC, which, in addition to the alpha1, alpha2/delta, beta core motif, also has an additional tightly associated integral membrane glycoprotein subunit termed gamma 1. Upon co-expression with the alpha1.1, alpha2/delta1, beta1a subunits of the skeletal muscle VDCC, gamma subunits alter the peak currents, and the kinetics of channel activation and inactivation with the overall effect being a normalisation of currents to those resembling the endogenous channel2. Together, these results suggest that gamma subunits modulate skeletal muscle VDCCs by stabilising their conformation. The gamma 2 subunits, or stargazin, the product of a gene mutated in the stargazer mouse, is a homolog of the gamma 1 channel and is selectively expressed in the brain. It is considered to be a putative neuronal Ca2+ channel subtype mainly based on its homology to the gamma 1.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CACNG2 (C-term) antibody

Western blot of rat synaptic membrane (SPM) showing specific immunolabeling of the ~ 36k stargazin protein. Rabbit IgG Aff - Purified Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CACNG2 (203-323, Cytopl. Dom.) antibody

WB of rat brain lysate showing detection of ~35 kDa TARP Gamma2/Stargazin protein using Anti-TARP Gamma2/Stargazin antibody.  Lane 1: MW ladder. Lane 2: Anti-TARP Gamma2 (1:100). Lane 3: Anti-TARP Gamma2 (1:250). Lane 4: Anti-TARP Gamma2 (1:500). Lane 5: Anti-TARP Gamma2 (1:1000).  Load: 20 µg RB lysate per lane. Block: 5% milk + TBST 1hr at RT. Primary antibody: Mouse Anti-TARP Gamma2 monoclonal antibody incubated for 60 min at RT. Secondary antibody: Goat Anti-Mouse HRP antibody at 1:50 for 60 min at RT. Colour Development: TMB solution for 30 min at RT. Predicted/Observed size: ~ 35 kDa. Other band(s) (unknown): ~60kDa, ~75kDa. Mouse IgG2a S245-1 Purified Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CACNG2 antibody

Western blot analysis of rat brain membranes: 1. Anti-Cav?2 antibody, (1:200). 2. Anti-Cav?2 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CACNG2 antibody

Immunoblot versus low-speed pellet samples from wild-type (WT) and Stargazer mutant (STG) mice and probed with N245/1 TC supe. Data courtesy of Susumu Tomita, Yale University. Mouse IgG2a N245/1 Supernatant Ms, Rt ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

CACNG2 antibody

Immunoblot versus low-speed pellet samples from wild-type (WT) and Stargazer mutant (STG) mice and probed with N245/1 TC supe. Data courtesy of Susumu Tomita, Yale University. Mouse IgG2a N245/1 Purified Ms, Rt ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

CACNG2 antibody

Western blot analysis using gamma2 antibody on rat brain lysate. Rabbit IgG Purified Hu WB
0.1 mg / €360.00
  Acris Antibodies GmbH

CACNG2 antibody

Western Blot analysis of CACNG2 expression in transfected 293T cell line (H00010369-T02) by CACNG2 MaxPab polyclonal antibody.

Lane 1: CACNG2 transfected lysate(35.53 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CACNG2 antibody

Western blot of rat synaptic membrane (SPM) showing specific immunolabeling of the ~ 36k Cacng2 protein. Using Cacng2 polyclonal antibody ( Cat # PAB9618 ). Rabbit Ms, Rt WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

CACNG2 antibody

Western blot analysis using Cacng2 polyclonal antibody on rat brain lysate. Rabbit Hu, Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CACNG2 antibody

Rat Liver; WB Suggested Anti-Cacng2 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Rat Liver; Cacng2 antibody - middle region (ARP35189_P050) in Rat Liver cells using Western Blot Rabbit Aff - Purified Hu, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CACNG2 antibody

Western blot analysis of CACNG2 expression in human brain (A); mouse brain (B); rat brain (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CACNG2 antibody

Western blot analysis of CACNG2 expression in human brain (A); mouse brain (B); rat brain (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CACNG2 antibody

Western blot analysis of CACNG2 expression in human brain (A); mouse brain (B); rat brain (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CACNG2 antibody

Western Blot: Stargazin Antibody [NB100-61089] - Rat synaptic membrane (SPM) showing specific immunolabeling of the ~ 36k stargazin protein. Rabbit IgG Aff - Purified Rt WB
0.1 ml / €380.00
  Novus Biologicals Inc.

CACNG2 antibody

CACNG2 Rabbit Serum Hu P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

CACNG2 antibody

CACNG2 Goat Purified Hu, Ms, Rt C, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

CACNG2/4/8 (203-323, Cytopl. Dom.) antibody

WB of rat brain lysate showing detection of ~35-55 kDa TARP Gamma2-4-8 (Stargazin) protein using Anti-Tarp Gamma2-4-8 antibody.  Lane 1: MW ladder. Lane 2: Anti-TARP Gamma2-4-8 (1:100). Lane 3: Anti-TARP Gamma2-4-8 (1:250). Lane 4: Anti-TARP Gamma2-4-8 (1:500). Lane 5: Anti-TARP Gamma2-4-8 (1:1000).  Load: 20 µg RB lysate per lane. Block: 5% milk + TBST 1hr at RT. Primary antibody: Mouse Anti-TARP Gamma2-4-8 monoclonal antibody incubated for 60 min at RT. Secondary antibody: Goat Anti-Mouse HRP antibody at 1:50 for 60 min at RT. Colour Development: TMB solution for 30 min at RT. Predicted/Observed size: ~ 55 kDa. Other band(s) (faint): ~37kDa, ~40kDa, ~75kDa. Mouse IgG2a S245-36 Purified Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CACNG2/4/8 antibody

Adult rat brain membrane immunoblot Mouse IgG2a N245/36 Supernatant Ms, Rt ICC/IF, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

CACNG2/4/8 antibody

Adult rat brain membrane immunoblot Mouse IgG2a N245/36 Purified Ms, Rt ICC/IF, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

Lysates

Catalog No.    

CACNG2 293T Cell Transient Overexpression Lysate(Denatured)

CACNG2 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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