CACNG3 antibody

Principal name

CACNG3 antibody

Alternative names for CACNG3 antibody

Voltage-dependent calcium channel gamma-3 subunit, Neuronal voltage-gated calcium channel gamma-3 subunit

SwissProt ID

O60359 (Human), Q0VD05 (Bovin), Q8VHX0 (Rat), Q9JJV5 (Mouse)

Gene ID

10368 (CACNG3), 140724 (Cacng3), 54376

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of CACNG3 antibody

Voltage-dependent calcium channels (VDCCs) are large (>400 kDa) heteromers which contain, minimally, three core subunits alpha1, alpha2/delta, beta in a 1:1:1 stoichiometry. Expression of VDCC gene products in Xenopus oocytes, or transfected cells shows that the alpha1 subunits contain the ion channel pore while the auxiliary alpha2/delta and beta subunits confer optimal cell surface expression and channel kinetics1. Until recently, the only exception to the above paradigm was the skeletal muscle VDCC, which, in addition to the alpha1, alpha2/delta, beta core motif, also has an additional tightly associated integral membrane glycoprotein subunit termed gamma 1. Upon co-expression with the alpha1.1, alpha2/delta1, beta1a subunits of the skeletal muscle VDCC, gamma subunits alter the peak currents, and the kinetics of channel activation and inactivation with the overall effect being a normalisation of currents to those resembling the endogenous channel. Together, these results suggest that gamma subunits modulate skeletal muscle VDCCs by stabilising their conformation. The gamma 3 subunit is specifically localized in the brain, with the gamma 2 and gamma 4 subunits. It shares >60% sequence homology with the gamma 2 and gamma 4 subunits and ~25% sequence homology with the gamma 1 and gamma 5 subunits.

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CACNG3 antibody

  Rabbit Polyclonal Anti-CaVgamma3  
Western blot analysis of rat brain (lanes 1 and 4), mouse brain (lanes 2 and 5) and human neuroblastoma (SH-SY5Y) cells (lanes 3 and 6): 1-3. Anti-CaV?3 antibody, (1:1000). 4-6. Anti-CaV?3 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CACNG3 antibody

  Rabbit Polyclonal Anti-Cacng3 Antibody  
WB Suggested Anti-Cacng3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Mouse Liver Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CACNG3 antibody

Western blot analysis using gamma3 antibody on rat brain lysate. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CACNG3 - human gene knockout kit via CRISPR

CACNG3 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CACNG3 - human gene knockout kit via CRISPR

CACNG3 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CACNG3 - human gene knockout kit via CRISPR

CACNG3 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cacng3 - mouse gene knockout kit via CRISPR

Cacng3 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cacng3 - mouse gene knockout kit via CRISPR

Cacng3 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cacng3 - mouse gene knockout kit via CRISPR

Cacng3 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cacng3 - mouse gene knockout kit via CRISPR

Cacng3 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CACNG3 overexpression lysate

CACNG3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CACNG3 (mGFP-tagged)-Human calcium channel, voltage-dependent, gamma subunit 3 (CACNG3), 200 uL, >10^7 TU/mL

Lenti ORF particles, CACNG3 (mGFP-tagged)-Human calcium channel, voltage-dependent, gamma subunit 3 (CACNG3), 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, CACNG3 (Myc-DDK-tagged)-Human calcium channel, voltage-dependent, gamma subunit 3 (CACNG3), 200 uL, >10^7 TU/mL

Lenti ORF particles, CACNG3 (Myc-DDK-tagged)-Human calcium channel, voltage-dependent, gamma subunit 3 (CACNG3), 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cacng3 (GFP-tagged) - Mouse calcium channel, voltage-dependent, gamma subunit 3 (Cacng3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cacng3 (GFP-tagged) - Mouse calcium channel, voltage-dependent, gamma subunit 3 (Cacng3), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Cacng3 (Myc-DDK-tagged) - Mouse calcium channel, voltage-dependent, gamma subunit 3 (Cacng3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cacng3 (Myc-DDK-tagged) - Mouse calcium channel, voltage-dependent, gamma subunit 3 (Cacng3), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cacng3 (GFP-tagged ORF) - Rat calcium channel, voltage-dependent, gamma subunit 3 (Cacng3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cacng3 (GFP-tagged ORF) - Rat calcium channel, voltage-dependent, gamma subunit 3 (Cacng3), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Cacng3 (Myc-DDK-tagged ORF) - Rat calcium channel, voltage-dependent, gamma subunit 3 (Cacng3), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cacng3 (Myc-DDK-tagged ORF) - Rat calcium channel, voltage-dependent, gamma subunit 3 (Cacng3), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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