Cadherin-11 antibody

Principal name

Cadherin-11 antibody

Alternative names for Cadherin-11 antibody

Osteoblast cadherin, OSF-4, CDH11, OB Cadherin

SwissProt ID

O93319 (Chick), P55287 (Human), P55288 (Mouse)

Gene ID

1009 (CDH11), 12552 (Cdh11)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F)

Background of Cadherin-11 antibody

Cadherins constitute a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. The cadherins generally contain five extracellular repeats, a transmembrane domain and a cytoplasmic tail that binds to the catenin family of cytoskeletal anchoring proteins which also function as signal transducers. The extracellular domains are responsible for the specificity of homophilic interactions between cells expressing the same cadherin. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4). Kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins. The progression of carcinomas is associated with the loss of epithelial morphology and a concomitant acquisition of a more mesenchymal phenotype, which is thought to contribute to the invasive and/or metastatic behavior. A putative role for cadherin-11 in these late stages of tumor progression is based on the fact that migration of mesenchymal cells is facilitated when cadherin-11 is highly expressed.

General readings

1. Canova C, Hashibe M, Simonato L, Nelis M, Metspalu A, Lagiou P, Trichopoulos D, Ahrens W, Pigeot I, Merletti F, Richiardi L, Talamini R, Barzan L, Macfarlane GJ, Macfarlane TV, Holcátová I, Bencko V, Benhamou S, Bouchardy C, Kjaerheim K, Lowry R, Agudo
Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project. Cancer research 2009 Apr 69 (7): 2956-65. PMID: 19339270

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cadherin-11 antibody

Western blot on a lysate of Cadherin 11 transfected PC3 cells Mouse IgG1 16A Purified Hu, Rt C, ICC/IF, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

Cadherin-11 (497-509) antibody

HEK293 lysate (10µg protein in RIPA buffer) overexpressing Human CDH11 with C-terminal MYC tag probed with AP21504PU-N (1µg/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with AP21504PU-N (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Rt E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Cadherin-11 (26-37) antibody

  Goat Anti-CDH11 (aa 26-37) Antibody  
HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human CDH11 with C-terminal MYC tag probed with TA311215 (1ug/ml) in Lane A and probed with anti-MYC Tag (1:1000) in Lane C. Mock-transfected HEK293 probed with TA311215 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cadherin-11 antibody

  Rabbit polyclonal anti-CDH11 antibody  
Western blot analysis of extracts from Jurkat cells, using CDH11 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cadherin-11 antibody

Western blot (WB) analysis of OB-cadherin antibody (Cat.-No.: AP01246PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Cadherin-11 antibody

Western blot analysis of extracts from Jurkat cells, using CDH11 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €230.00
  Assay Biotech

Cadherin-11 antibody

Western blot analysis of extracts from Jurkat cells, using CDH11 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

CDH11 - human gene knockout kit via CRISPR

CDH11 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CDH11 - human gene knockout kit via CRISPR

CDH11 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CDH11 - human gene knockout kit via CRISPR

CDH11 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CDH11 - human gene knockout kit via CRISPR

CDH11 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cdh11 - mouse gene knockout kit via CRISPR

Cdh11 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cdh11 - mouse gene knockout kit via CRISPR

Cdh11 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cdh11 - mouse gene knockout kit via CRISPR

Cdh11 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cdh11 - mouse gene knockout kit via CRISPR

Cdh11 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Cadherin-11

  Recombinant protein of human cadherin 11, type 2, OB-cadherin (osteoblast) (CDH11)  
Cadherin-11 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Cadherin-11

  Purified recombinant protein of Human cadherin 11, type 2, OB-cadherin (osteoblast) (CDH11)  
Cadherin-11 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CDH11 overexpression lysate

CDH11 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cdh11 (GFP-tagged) - Mouse cadherin 11 (Cdh11), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cdh11 (GFP-tagged) - Mouse cadherin 11 (Cdh11), 200 uL, >10^7 TU/mL  
200 µl / €1,510.00
  OriGene Technologies, Inc.

Lenti ORF particles, Cdh11 (Myc-DDK-tagged) - Mouse cadherin 11 (Cdh11), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cdh11 (Myc-DDK-tagged) - Mouse cadherin 11 (Cdh11), 200 uL, >10^7 TU/mL  
200 µl / €1,360.00
  OriGene Technologies, Inc.

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