Cadherin-4 antibody

Principal name

Cadherin-4 antibody

Alternative names for Cadherin-4 antibody

CDH4, R-CAD, Retinal Cadherin, R Cadherin, Cadherin R

SwissProt ID

P24503 (Chick), P39038 (Mouse), P55283 (Human), Q63149 (Rat)

Gene ID

1002 (CDH4), 12561 (Cdh4)

Available reactivities

Hu (Human), Chk (Chicken), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of Cadherin-4 antibody

CDH4 gene is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Maeda,M., (2006) Oncogene 25 (33), 4595-4604

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cadherin-4 antibody

  CDH4 mouse monoclonal antibody, clone OTI4F5 (formerly 4F5)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CDH4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804735) Mouse IgG1 OTI4F5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cadherin-4 antibody

  CDH4 mouse monoclonal antibody, clone OTI6H5 (formerly 6H5)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-CDH4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804816) Mouse IgG1 OTI6H5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cadherin-4 (N-term) antibody

  Rabbit polyclonal CDH4 Antibody (N-term)  
Western blot analysis of anti-CDH4 Antibody (N-term) (RB13654) in HepG2 cell line lysates (35ug/lane). CDH4(arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu F, ICC/IF, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Cadherin-4 antibody

  CDH4 mouse monoclonal antibody, clone OTI3C10 (formerly 3C10)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDH4 (RC210970, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDH4. Mouse IgG2a OTI3C10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cadherin-4 antibody

  CDH4 mouse monoclonal antibody, clone OTI4H2 (formerly 4H2)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-CDH4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804743) Mouse IgG1 OTI4H2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cadherin-4 antibody

  CDH4 mouse monoclonal antibody, clone OTI1B7 (formerly 1B7)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDH4 (RC210970, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDH4. Mouse IgG2b OTI1B7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cadherin-4 antibody

  CDH4 mouse monoclonal antibody, clone OTI4D9 (formerly 4D9)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDH4 (RC210970, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDH4. Mouse IgG2a OTI4D9 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cadherin-4 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CDH4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P
50 µg / €230.00
  Assay Biotech

Cadherin-4 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CDH4 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

CDH4 - human gene knockout kit via CRISPR

CDH4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CDH4 - human gene knockout kit via CRISPR

CDH4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CDH4 - human gene knockout kit via CRISPR

CDH4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CDH4 - human gene knockout kit via CRISPR

CDH4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cdh4 - mouse gene knockout kit via CRISPR

Cdh4 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cdh4 - mouse gene knockout kit via CRISPR

Cdh4 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cdh4 - mouse gene knockout kit via CRISPR

Cdh4 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cdh4 - mouse gene knockout kit via CRISPR

Cdh4 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CDH4 overexpression lysate

CDH4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CDH4 (mGFP-tagged) - Human cadherin 4, type 1, R-cadherin (retinal) (CDH4), 200 uL, >10^7 TU/mL

Lenti ORF particles, CDH4 (mGFP-tagged) - Human cadherin 4, type 1, R-cadherin (retinal) (CDH4), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, CDH4 (Myc-DDK tagged) - Human cadherin 4, type 1, R-cadherin (retinal) (CDH4) , 200 uL, >10^7 TU/mL

Lenti ORF particles, CDH4 (Myc-DDK tagged) - Human cadherin 4, type 1, R-cadherin (retinal) (CDH4) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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