Calcipressin-1 antibody

Principal name

Calcipressin-1 antibody

Alternative names for Calcipressin-1 antibody

RCAN1, ADAPT78, CSP1, DSC1, DSCR1, Regulator of calcineurin 1, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1

SwissProt ID

P53805 (Human), Q3ZBP4 (Bovin), Q6IN33 (Rat), Q9JHG6 (Mouse)

Gene ID

1827 (RCAN1), 54720 (Rcan1), 266766

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), African clawed frog, Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Sh (Sheep), Ze (Zebrafish)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Paraffin Sections (P)

Background of Calcipressin-1 antibody

RCAN1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.

General readings

Genesca L., et al. (2003) J Biol Chem. Sep 1;374.
Hesser BA., et al. (2004) Blood Jul 1;104(1):149-58.
Harris CD., et al. (2007) FEBS J. Apr;274(7):1715-24.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Calcipressin-1 antibody

  Rabbit Polyclonal Anti-RCAN1 Antibody  
RCAN1 antibody - middle region validated by WB using MOUSE OSTEOCLASTS at 1: 1000. Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Calcipressin-1 antibody

  Rabbit Polyclonal RCAN1 Antibody  
Western Blot: RCAN1 Antibody - Western blot analysis of RCAN in human fetal brain using anti-RCAN1. Rabbit Purified Hu, Ms, Rt C, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Calcipressin-1 antibody

  Goat Anti-Calcipressin-1 (RCAN1) Antibody  
(1ug/ml) staining of Mouse Brain and KO Mouse Brain lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Calcipressin-1 antibody

  Rabbit polyclonal anti-RCAN1 antibody  
Western blot analysis of extracts from HeLa cells, using RCAN1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Calcipressin-1 (N-term) antibody

  Rabbit polyclonal RCAN1 Antibody (N-term)  
RCAN1 Antibody (N-term) (Cat. #TA324606) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the RCAN1 antibody detected the RCAN1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Calcipressin-1 antibody

  Rabbit Polyclonal anti-Rcan1 Antibody  
Calcipressin-1 Rabbit IgG Purified Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Calcipressin-1 antibody

  Rabbit anti-RCAN1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using RCAN1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Calcipressin-1 antibody

  Rabbit Polyclonal Anti-RCAN1 Antibody - N-terminal region  
WB Suggested Anti-RCAN1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Placenta Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Calcipressin-1 antibody

  Rabbit Polyclonal Anti-RCAN1 Antibody  
Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Mouse heart tissue, Mouse brain tissue, Primary antibody: (RCAN1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Calcipressin-1 (Center) antibody

TOP: The anti-DSCR1 Pab is used in Western blot to detect DSCR1 in endothelial cell lysate. BOTTOM: Endothelial cell lysate transferred to membrane was incubated with primary antibody at a 1:500 dilution in 2% BSA in TBST at 4¢ªC overnight. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Calcipressin-1 (C-term) antibody

TOP: The anti-DSCR1 Pab is used in Western blot to detect DSCR1 in endothelial tissue lysate. BOTTOM: Endothelial cell lysate transferred to membrane was incubated with primary antibody at a 1:500 dilution in 2% BSA in TBST at 4¢ªC overnight. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

RCAN1 - human gene knockout kit via CRISPR

RCAN1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

RCAN1 - human gene knockout kit via CRISPR

RCAN1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

RCAN1 - human gene knockout kit via CRISPR

RCAN1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

RCAN1 - human gene knockout kit via CRISPR

RCAN1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Calcipressin-1 (transcript variant 1)

  Recombinant protein of human regulator of calcineurin 1 (RCAN1), transcript variant 1  
Calcipressin-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Calcipressin-1 (full length, N-term HIS tag, transcript variant 3)

  Purified recombinant protein of Human regulator of calcineurin 1 (RCAN1), transcript variant 3, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug  
Calcipressin-1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Calcipressin-1 (N-term HIS tag, transcript variant 2)

  Purified recombinant protein of Human regulator of calcineurin 1 (RCAN1), transcript variant 2, with N-terminal HIS tag, expressed in E.Coli, 50ug  
Calcipressin-1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Calcipressin-1 (Isoform B) (1-117)

Calcipressin-1 Human Purified > 90 % >/= 90% by SDS PAGE E. coli
0.5 mg / €1,000.00
  Acris Antibodies GmbH

Calcipressin-1 (Isoform B) (1-117)

Calcipressin-1 Human Purified > 90 % >/= 90% by SDS PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

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