CALHM1 / FAM26C antibody

Principal name

CALHM1 / FAM26C antibody

Alternative names for CALHM1 / FAM26C antibody

Calcium homeostasis modulator protein 1

SwissProt ID

Q8IU99 (Human)

Gene ID

255022 (CALHM1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CALHM1 / FAM26C antibody

A misbalance in Ca2+ homeostasis seems to be related to the development of Alzheimerâ??s disease (AD). Indeed Neurol Ca2+ balance may affect the levels of proteins associated with AD, such as amyloid-beta (Ab) and tau. Calcium homeostasis modulator 1 (CALHM1) is a cerebral Ca2+ channel component responsible for controlling intracellular Ca2+ levels and Ab metabolism. CALHM1 is a three transmembrane glycoprotein, mostly localized to the endoplasmic reticulum (ER) although it can be detected at the plasma membrane. A functiol channel is formed by multiple subunits which has some structural similarities to the NMDA receptor. It is expressed in all brain regions. In cultured cells, overexpression of CALHM1 increases intracellular Ca2+ levels and reduces Ab accumulation, thereby reinforcing its implication in the development of AD. Indeed, a polymorphism in the gene was found to affect the onset of AD.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CALHM1 / FAM26C antibody

Western blot analysis of CALHM1 in rat liver tissue lysate with CALHM1 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CALHM1 / FAM26C antibody

Western blot analysis of rat brain (lanes 1 and 4), mouse brain (lanes 2 and 5), U-87 MG (lanes 3 and 6) and C6 (lanes 4 and 8) lysates: 1. Anti-Calcium Homeostasis Modulator 1 antibody, (1:200). 2. Anti-Calcium Homeostasis Modulator 1 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CALHM1 / FAM26C antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CALHM1 (RC206902, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CALHM1. Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CALHM1 / FAM26C Control Peptide

CALHM1 / FAM26C
50 µg / €160.00
  Acris Antibodies GmbH

CALHM1 / FAM26C antibody

CALHM1 / FAM26C Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

CALHM1 / FAM26C antibody

Western blot analysis of CALHM1 expression in human brain (A); rat brain (B) whole cell lysates. Rabbit Aff - Purified Hu, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CALHM1 / FAM26C antibody

Western blot analysis of CALHM1 expression in human brain (A); rat brain (B) whole cell lysates. Rabbit Aff - Purified Hu, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CALHM1 / FAM26C antibody

Western blot analysis of CALHM1 expression in human brain (A); rat brain (B) whole cell lysates. Rabbit Aff - Purified Hu, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CALHM1 / FAM26C antibody

CALHM1 / FAM26C Rabbit Hu E, WB
50 µg / €400.00
  Novus Biologicals Inc.

CALHM1 / FAM26C antibody

Immunohistochemistry-Paraffin: CALHM1 Antibody [NBP1-77112] - Rat liver tissue with CALHM1 antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

CALHM1 / FAM26C antibody

Immunohistochemistry-Paraffin: CALHM1 Antibody [NBP1-83930] - Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Lysates

Catalog No.    

CALHM1 overexpression lysate

CALHM1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

12 Item(s)

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