Calmodulin antibody

Principal name

Calmodulin antibody

Alternative names for Calmodulin antibody

CALM1, CALM, CAM, CAM1

SwissProt ID

P02599 (Dicdi), P62149 (Chick), P62157 (Bovin), P62158 (Human), P62161 (Rat), P62204 (Mouse), Q6PI52, Q6YNX6 (Sheep)

Gene ID

801 (CALM1), 100297344 (CALM2), 8622104 (calA), 808 (CALM3), 3392785, 805

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bac (Bacteria), Bov (Bovine), Chk (Chicken), Ze (Zebrafish), Rb (Rabbit), Sh (Sheep)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Frozen Sections (C)

Background of Calmodulin antibody

Calmodulin, calcium-modulated protein, is a calcium-binding protein expressed in all eukaryotic cells. It can bind to and regulate a number of different protein targets, thereby affecting many different cellular functions. Calmodulin mediates processes such as inflammation, metabolism, apoptosis, smooth muscle contraction, intracellular movement, short-term and long-term memory, nerve growth and the immune response. Calmodulin is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes. Many of the proteins that Calmodulin binds are unable to bind calcium themselves, and as such use Calmodulin as a calcium sensor and signal transducer. Calmodulin can also make use of the calcium stores in the endoplasmic reticulum, and the sarcoplasmic reticulum. Calmodulin undergoes a conformational change upon binding to calcium, which enables it to bind to specific proteins for a specific response. Calmodulin can bind up to four calcium ions, and can undergo post-translational modifications, such as phosphorylation, acetylation, methylation and proteolytic cleavage, each of which has potential to modulate its actions. Calmodulin can also bind to edema factor toxin from the anthrax bacteria. Calmodulin is the archetype of the family of calcium-modulated proteins of which nearly 20 members have been found. Calmodulin contains 149 amino acids and has 4 calcium-binding domains. Its functions include roles in growth and the cell cycle as well as in signal transduction and the synthesis and release of neurotransmitters. Three calmodulin genes (CALM1, CALM2, and CALM3) map to chromosomes 14q24-q31, 2p21.1-p21.3, and 19q13.2-q13.3, respectively.

General readings

This product has been used in:Hulen D et al. Production and specificity of monoclonal antibodies against calmodulin from Dictyostelium discoideum. Cell Motil Cytoskeleton 18:113-22 (1991). PubMed PMID: 2013107
General / background references:Zhu Q et al. Calmodulin and the contractile vacuole complex in mitotic cells of Dictyostelium discoideum. J Cell Sci 104 (Pt 4):1119-27 (1993). PubMed PMID: 8314896
Zhu Q & Clarke M Association of calmodulin and an unconventional myosin with the contractile vacuole complex of Dictyostelium discoideum. J Cell Biol 118:347-58 (1992). PubMed PMID: 1629238
Coling DE & Salisbury JL Characterization of the calcium-binding contractile protein centrin from Tetraselmis striata (Pleurastrophyceae). J Protozool 39:385-91 (1992). PubMed PMID: 1640386
Clarke M et al. Density-dependent induction of discoidin-I synthesis in exponentially growing cells of Dictyostelium discoideum. Differentiation 34:79-87 (1987). PubMed PMID: 3622952

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Calmodulin antibody

Calmodulin Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Calmodulin antibody

Western blot analysis of Calmodulin expression in NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Calmodulin antibody

Immunohistochemistry: AM03186PU-N Calmodulin antibody staining of Formalin-Fixed, Paraffin-Embedded Human Brain, Cerebellum at 10 µg/ml after heat-induced antigen retrieval. Mouse IgG2a J4D8 Aff - Purified Hu E, P, WB
0.1 ml / €320.00
  Acris Antibodies GmbH

Calmodulin antibody

Immunohistochemistry: AM03186PU-N Calmodulin antibody staining of Formalin-Fixed, Paraffin-Embedded Human Brain, Cerebellum at 10 µg/ml after heat-induced antigen retrieval. Mouse IgG2a J4D8 Aff - Purified Hu E, P, WB
50 µl / €230.00
  Acris Antibodies GmbH

Calmodulin antibody

Calmodulin Mouse IgG1 CM-16 Purified Chk, Hu, Rt WB
0.1 mg / €340.00
  Acris Antibodies GmbH

Calmodulin antibody

Calmodulin Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Calmodulin (C-term) antibody

Formalin-fixed and paraffin-embedded human brain tissue reacted with Calmodulin antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms, Rt, Ze P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Calmodulin (C-term) antibody

Western blot analysis of CALM1 Antibody (C-term) (CAP17918PU-N) in Hela cell line lysates (35ug/lane). CALM1 (arrow) was detected using the purified Pab.(2ug/ml) Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Calmodulin pThr79/Ser81 antibody

Western blot analysis of extracts from HeLa tissue using Calmodulin (Phospho-Thr79/Ser81) antibody AP55927PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €340.00
  Acris Antibodies GmbH

Calmodulin pThr79/Ser81 antibody

Western blot analysis of extracts from HeLa tissue using Calmodulin (Phospho-Thr79/Ser81) antibody AP55927PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €270.00
  Acris Antibodies GmbH

Calmodulin antibody

Calmodulin Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Calmodulin antibody

Western Blot analysis of CALM2 expression in transfected 293T cell line (H00000805-T01) by CALM2 MaxPab polyclonal antibody.

Lane 1: CALM2 transfected lysate(16.5 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Calmodulin antibody

Calmodulin Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Calmodulin antibody

Immunofluorescence of monoclonal antibody to CALM2 on HeLa cell . [antibody concentration 10 ug/ml] Mouse IgG1 3F4-G5 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Calmodulin antibody

Western Blot analysis of CALM3 expression in transfected 293T cell line (H00000808-T01) by CALM3 MaxPab polyclonal antibody.

Lane 1: CALM3 transfected lysate(16.39 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Calmodulin antibody

Western Blot analysis of CALM3 expression in transfected 293T cell line (H00000808-T01) by CALM3 MaxPab polyclonal antibody.

Lane 1: CALM3 transfected lysate(16.39 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Calmodulin antibody

Detection limit for recombinant GST tagged CALM3 is 0.03 ng/ml as a capture antibody. Mouse IgG1 1E2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Calmodulin antibody

Calmodulin Mouse IgG1 CM-16 Chk, Hu, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Calmodulin antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with CALM1 polyclonal antibody ( Cat # PAB3927 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

Calmodulin pThr79/pSer81 antibody

Immunohistochemistry analysis of paraffin-embedded human brain, using Calmodulin (Phospho-Thr79+Ser81) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

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