Calmodulin antibody

Principal name

Calmodulin antibody

Alternative names for Calmodulin antibody

CALM1, CALM, CAM, CAM1

SwissProt ID

P02599 (Dicdi), P62149 (Chick), P62157 (Bovin), P62158 (Human), P62161 (Rat), P62204 (Mouse), Q6PI52, Q6YNX6 (Sheep)

Gene ID

801 (CALM1), 100297344 (CALM2), 8622104 (calA), 808 (CALM3), 805, 12313 (Calm1), 12314 (Calm2), 12315 (Calm3), 50663, 24242, 24244

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Chk (Chicken), Bov (Bovine), Rb (Rabbit), Sh (Sheep)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunoprecipitation (IP)

Background of Calmodulin antibody

Calmodulin, calcium-modulated protein, is a calcium-binding protein expressed in all eukaryotic cells. It can bind to and regulate a number of different protein targets, thereby affecting many different cellular functions. Calmodulin mediates processes such as inflammation, metabolism, apoptosis, smooth muscle contraction, intracellular movement, short-term and long-term memory, nerve growth and the immune response. Calmodulin is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes. Many of the proteins that Calmodulin binds are unable to bind calcium themselves, and as such use Calmodulin as a calcium sensor and signal transducer. Calmodulin can also make use of the calcium stores in the endoplasmic reticulum, and the sarcoplasmic reticulum. Calmodulin undergoes a conformational change upon binding to calcium, which enables it to bind to specific proteins for a specific response. Calmodulin can bind up to four calcium ions, and can undergo post-translational modifications, such as phosphorylation, acetylation, methylation and proteolytic cleavage, each of which has potential to modulate its actions. Calmodulin can also bind to edema factor toxin from the anthrax bacteria. Calmodulin is the archetype of the family of calcium-modulated proteins of which nearly 20 members have been found. Calmodulin contains 149 amino acids and has 4 calcium-binding domains. Its functions include roles in growth and the cell cycle as well as in signal transduction and the synthesis and release of neurotransmitters. Three calmodulin genes (CALM1, CALM2, and CALM3) map to chromosomes 14q24-q31, 2p21.1-p21.3, and 19q13.2-q13.3, respectively.

General readings

Berchtold, M. W.; Egli, R.; Rhyner, J. A.; Hameister, H.; Strehler, E. E. : Localization of the human bona fide calmodulin genes CALM1, CALM2, and CALM3 to chromosomes 14q24-q31, 2p21.1-p21.3, and 19q13.2-q13.3. Genomics 16: 461-465, 1993.

7 Item(s)

per page

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Calmodulin

  Recombinant protein of human calmodulin 3 (phosphorylase kinase, delta) (CALM3)  
Calmodulin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Calmodulin

  Recombinant protein of human calmodulin 2 (phosphorylase kinase, delta) (CALM2)  
Calmodulin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Calmodulin

Calmodulin Bovine Purified Purified by ion-exchange chromatography followed by gel-filtration. - > 95%. Determined by SDS-PAGE.
1 mg / €420.00
  Acris Antibodies GmbH

Calmodulin (1-149) (recombinant)

Calmodulin Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

Calmodulin (1-149) (recombinant)

Calmodulin Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Calmodulin

Calmodulin Bovine Purified > 95 % Brain
1 mg / €310.00
  HyTest Ltd.

Calmodulin

Calmodulin Human Purified > 95 % Brain
1 mg / €360.00
  HyTest Ltd.

7 Item(s)

per page
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