Calpain-1 antibody

Principal name

Calpain-1 antibody

Alternative names for Calpain-1 antibody

Calpain mu-type, muCANP, CAPN1, CANPL1, PIG30, CANP1, Calpain-1 catalytic subunit, Calpain-1 large subunit, Calcium-activated neutral proteinase 1, Micromolar-calpain, Cell proliferation-inducing gene 30 protein

SwissProt ID

O35350 (Mouse), P06815 (Rabit), P07384 (Human), P97571 (Rat), Q27970 (Bovin)

Gene ID

823 (CAPN1), 29153 (Capn1), 12333

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Rb (Rabbit), Por (Porcine), Eq (Equine), Gt (Goat), Sh (Sheep), Ze (Zebrafish), Can (Canine), GP (Guinea Pig)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Calpain-1 antibody

Calpain is a calcium-dependent thiol proteise that is functiolly active as a heterodimer composed of a small regulatory subunit and one of at least two large catalytic subunits (calpain 1 or calpain 2). In vitro, calpain 1 (mu-calpain) requires micromolar levels of calcium, while calpain 2 (M-calpain) requires millimolar levels of calcium for activation. The regulation of calpain in vivo is the subject of many current studies, which suggest that proteolytic activity is regulated post-transcriptiolly by mechanisms such as calcium requirements, subcellular localization of the heterodimer, phosphorylation via the EGFR-Erk sigling cascade, endogenous inhibitors (calpastatin) and autoproteolytic cleavage. Calpastatin negatively regulates autoproteolytic cleavage of calpain 1 between Gly27 and Leu28. Calpain influences cell migration by modifying rather than degrading its substrates responsible for cell adhesion and cytoskeletal arrangement. Control of calpain activity has caught the attention of drug development since limiting its activity could mute invasiveness of tumors or chronic inflammation.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Calpain-1 antibody

AP32722PU-N Calpain-1 Antibody staining of Human Spleen lysate at 0.3µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Calpain-1 (468-481) antibody

AP32723PU-N Calpain-1 Antibody staining of Human Kidney lysate at  0.3µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Por WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Calpain-1 antibody

Western blot analysis of Calpain 1 expression in lysate from Jurkat cells treated with (Lane 2) or without (Lane 1) camptothecin. Rabbit Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Calpain-1 antibody

Western blot analysis of Human fetal kidney tissue using TA324115(CAPN1 Antibody) at dilution 1/500 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Calpain-1 antibody

Western blot analysis of 293T cell using TA324116(CAPN1 Antibody) at dilution 1/450 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Calpain-1 antibody

Western blot analysis of extracts of various cell lines, using CAPN1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Calpain-1 antibody

CAPN1 antibody validated by WB using HT1080 cell lysate at 1ug/mL. Rabbit IgG Purified Bov, Eq, Gt, Hu, Ms, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Calpain-1 antibody

WB Suggested Anti-CAPN1 Antibody; Titration: 1.0 ug/ml; Positive Control: Fetal Brain Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Calpain-1 antibody

Calpain-1 Mouse IgG1 15C10 Purified Bov, Hu, Ms, Rt E, IP, P, WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Calpain-1 antibody

CAPN1 polyclonal antibody (A01), Lot # 050913JC01 Western Blot analysis of CAPN1 expression in Jurkat ( Cat # L017V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Calpain-1 antibody

Immunofluorescence of purified MaxPab antibody to CAPN1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

Calpain-1 antibody

Calpain-1 Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

Calpain-1 antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between CAPN1 and F2R. HeLa cells were stained with anti-CAPN1 rabbit purified polyclonal 1:1200 and anti-F2R mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Calpain-1 antibody

Calpain-1 Mouse IgG1 15C10 Bov, Hu, Ms, Rt E, IP, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Calpain-1 antibody

Western blot analysis of Capn1 expression in lysate from Jurkat cells treated with ( Lane 2 ) or without ( Lane 1 ) camptothecin. Rabbit Bov, Hu, Ms, Rb, Rt WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Calpain-1 antibody

Human HT1080; CAPN1 antibody - middle region (ARP60936_P050) validated by WB using HT1080 cell lysate at 1ug/mL.; CAPN1 antibody - middle region (ARP60936_P050) in Human HT1080 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Calpain-1 (N-term) antibody

Human Fetal Brain; WB Suggested Anti-CAPN1 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Fetal Brain; CAPN1 antibody - N-terminal region (ARP60937_P050) in Human Fetal Brain cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Calpain-1 antibody

Calpain-1 Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Calpain-1

Calpain-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Calpain-1

Calpain-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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