Calpain-6 antibody

Principal name

Calpain-6 antibody

Alternative names for Calpain-6 antibody

Calpamodulin, CAPN6, CALPM, CANPX, Calpain-like protease X-linked

SwissProt ID

O35646 (Mouse), O88501 (Rat), Q9Y6Q1 (Human)

Gene ID

827 (CAPN6), 83685 (Capn6)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunohistochemistry (IHC), Enzyme Immunoassay (E)

Background of Calpain-6 antibody

Calpains make up a ubiquitously expressed, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. This large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes as their activation can be triggered by calcium influx and oxidative stress. Calpain 6 (CAPN6) is most similar to Calpain 5; the C-terminal region of CAPN6 lacks homology to the calmodulin-like domain of other vertebrate calpains. CAPN6 is thought to be involved in the regulation of microtubule dynamics and cytoskeletal organization. CAPN6 has also been recently identified as an HIV dependency factor (HDF), suggesting that CAPN6 may be an important drug target in HIV treatment.

4 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Calpain-6 antibody

  Rabbit Polyclonal CAPN6 Antibody  
Western blot analysis of CAPN6 in rat lung tissue lysate with CAPN6 antibody at (A) 0.5 and (B) 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Calpain-6 antibody

  Anti-CAPN6 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, Nucleus. Positive control: Human esophagus cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CAPN6 antibody at dilution 1/15, on the right is treated with the fusion protein. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Calpain-6 (C-term) antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Calpain-6 (Center) antibody

CAPN6 Antibody (Center) (Cat. #AP50726PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CAPN6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

4 Item(s)

per page
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