Calsequestrin-1 antibody

Principal name

Calsequestrin-1 antibody

Alternative names for Calsequestrin-1 antibody

Calmitin, CASQ1, CASQ, Calsequestrin skeletal muscle isoform

SwissProt ID

O09165 (Mouse), P07221 (Rabit), P19204 (Chick), P19633 (Rat), P31236 (Canfa), P31415 (Human)

Gene ID

100009095 (CASQ1), 844, 844165 (GRF2)

Available reactivities

Can (Canine), Ms (Mouse), Rb (Rabbit), Hu (Human), Rt (Rat), Sh (Sheep), Chk (Chicken), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of Calsequestrin-1 antibody

The sarcoplasmic reticulum (SR) is in part responsible for maintaining the level of intracellular calcium in cardiac and skeletal muscle by storing and releasing calcium. Several intralumenal SR calcium binding proteins have been identified, the most prominent of these is calsequestrin. Calsequestrin is a calcium binding protein known to sequester calcium accumulated in the sarcoplasmic reticulum of muscle cells during relaxation and is found discretely localized to the junctional and corbular (terminal cisternae) SR. Calsequestrin functions to localize calcium near the junctional face of the terminal cisternae from which calcium can be released into the cytosol via the ryanodine receptor. This protein is highly acidic and has a large capacity and moderate to low affinity for calcium. Two mammalian isoforms of calequestrin exist, a cardiac and a skeletal muscle isoform, which are the products of different genes and are 63% identical.

General readings

This product has been used in:Knudson CM et al. Specific absence of the alpha 1 subunit of the dihydropyridine receptor in mice with muscular dysgenesis. J Biol Chem 264:1345-8 (1989). PubMed PMID: 2536362
General / background references:Moore RA et al. A transgenic myogenic cell line lacking ryanodine receptor protein for homologous expression studies: reconstitution of Ry1R protein and function. J Cell Biol 140:843-51 (1998). PubMed PMID: 9472036
Milner RE et al. Calcium binding proteins in the sarcoplasmic/endoplasmic reticulum of muscle and nonmuscle cells. Mol Cell Biochem 112:1-13 (1992). PubMed PMID: 1513330
Ohlendieck K et al. Analysis of excitation-contraction-coupling components in chronically stimulated canine skeletal muscle. Eur J Biochem 202:739-47 (1991). PubMed PMID: 1662614

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Calsequestrin-1 antibody

Calsequestrin 1 antibody detects CASQ1 protein by Western blot analysis. A. 30 ug GL261 whole cell lysate/extract. B. 30 ug Raw264.7 whole cell lysate/extract. C. 30 ug C2C12 whole cell lysate/extract. 10 % SDS-PAGE. Calsequestrin 1 antibody (TA308862) di Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Calsequestrin-1 antibody

Calsequestrin-1 Mouse IgG3 1D7 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

Calsequestrin-1 antibody

Calsequestrin-1 Mouse IgG2b VIIID12 Ascites Can, Chk, Hu, Ms, Por, Rb ICC/IF, IP, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Calsequestrin-1 antibody

Calsequestrin-1 Rabbit IgG Aff - Purified Can, Hu, Ms, Rt, Sh IP, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Calsequestrin-1 antibody

Western Blot: calsequestrin 1 Antibody [NBP1-31597] - Western Blot analysis of NBP1-31597 on H1299 (Lane A), HeLa S3 (Lane B), and Hep G2 (Lane C), with 10% SDS PAGE, diluted at 1:1000. Rabbit IgG Hu P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Calsequestrin-1

Calsequestrin-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Calsequestrin-1

Calsequestrin-1 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Calsequestrin-1

Calsequestrin-1 Human
10 µg / €380.00
  Abnova Taiwan Corp.

Calsequestrin-1

Calsequestrin-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue
10 µg / €380.00
  Abnova Taiwan Corp.

Calsequestrin-1

Calsequestrin-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CASQ1 overexpression lysate

CASQ1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

11 Item(s)

per page
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