CAMP / CAP18 antibody

Principal name

CAMP / CAP18 antibody

Alternative names for CAMP / CAP18 antibody

Cathelicidin antimicrobial peptide, FALL39, FALL-39, HSD26, CAP-18, hCAP-18, Antibacterial protein LL-37, 18 kDa cationic antimicrobial protein

SwissProt ID

P49913 (Human)

Gene ID

820 (CAMP)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP)

Background of CAMP / CAP18 antibody

Antimicrobial peptides (AMP) are effector molecules of the innate immune system with direct antimicrobioal and immunomodulatory effects. AMP are produced by epithelial and professional host defense cells such as macrophages or neutrophils. AMP directly inactivate microorganisms and, in addition, have diverse activities on various cell types. In mammals, peptides of the defensin and the cathelicidin families are found.  hCAP-18 is the only cathelicidin present in humans. hCAP-18 is a 170 amino acid cathelicidin anti-microbial precursor protein that is proteolytically processed to yield the antibacterial peptide LL-37. The precursor hCAP-18 is found in the specific granules of neutrophils and is expressed in many immune and epithelial cells. Cathelicidin has an established role in host defense. In addition to their direct antimicrobial function, cathelicidin peptides are involved in the modulation of repair and tissue homeostasis, epithelial wound healing, chemoattraction of immune cells, and release of inflammatory mediators from epithelial cells. Recent studies also found that LL-37 significantly regulates endocytic capacity, modifies expression of phagocytic receptors, increases secretion of Th1-inducing cytokines of dendritic cells (DC) generated from blood monocytes, and modulates the response of monocytes and DC to toll like receptor (TLR)–ligands. Moreover LL-37 also modulates the response of neutrophils to bacterial activation.
Structure: 170 amino acids with predicted molecular weight of 19.3 kD.
Distribution: Secreted.
Function: It is an antimicrobial protein found in specific granules of polymorphonuclear leukocytes. It binds to bacterial lipopolysaccharides (LPS) and has antibacterial activity.

General readings

Nijnik,A.,et al. (2012) J. Leukoc. Biol. 91 (4), 599-607Rosen,G., et al. (2012) Infect. Immun. 80 (3), 1107-1114

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CAMP / CAP18 antibody

Western blot analysis of Cathelicidin in Human spleen tissue lysate with Cathelicidin antibody at 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CAMP / CAP18 antibody

Immunofluorescence: Cathelicidin Antibody (OSX12) [NBP1-46781] - IF on ethanol-fixed human spermatosoid using Mouse monoclonal to human Cathelicidin (CAP-18, antibacterial protein LL-37, CAMP, CRAMP, FALL39): OSX12 clone  at a concentration of 10 µg/ml. DAPI counterstained appearing in blue. Mouse IgG1 OSX12 Purified Hu F, ICC/IF, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

CAMP / CAP18 (C-term) antibody

Anti-CAMP antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. Rabbit Purified Hu, Ms, Rt E, P, WB
50 µg / €345.00
  OriGene Technologies, Inc.

CAMP / CAP18 antibody

Western blot analysis of extracts of mouse liver cell lines, using CAMP antibody. Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CAMP / CAP18 antibody

Western blot analysis of Neutrophil cells using anti-CAP-18 antibody (clone H7). Mouse IgG1 H7 Purified Hu F, ICC/IF, IP, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CAMP / CAP18 Control Peptide

CAMP / CAP18
50 µg / €160.00
  Acris Antibodies GmbH

CAMP / CAP18 antibody

CAMP MaxPab polyclonal antibody. Western Blot analysis of CAMP expression in human spleen. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CAMP / CAP18 antibody

CAMP / CAP18 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

CAMP / CAP18 antibody

Immunohistochemistry of CAMP in human spleen tissue with CAMP polyclonal antibody ( Cat # PAB13021 ) at 5 µg/ml. Rabbit Hu, Ms, Rt P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CAMP / CAP18 antibody

Cathelicidin antibody [H7] Mouse IgG1 H7 Purified Hu ICC/IF, WB
0.1 ml / €400.00
  Immuquest

CAMP / CAP18 antibody

Immunohistochemistry-Paraffin: Cathelicidin Antibody [NBP1-76864] - Human spleen tissue with Cathelicidin antibody at 5 ug/mL._x000d_ Rabbit Aff - Purified Hu E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CAMP / CAP18

CAMP / CAP18 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CAMP / CAP18 (34-173, His-tag)

CAMP / CAP18 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

CAMP / CAP18 (34-173, His-tag)

CAMP / CAP18 Human Purified > 90 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

CAMP / CAP18

CAMP / CAP18 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CAMP 293T Cell Transient Overexpression Lysate(Denatured)

CAMP 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

16 Item(s)

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