cAMP / cyclic AMP antibody

Principal name

cAMP / cyclic AMP antibody

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Sheep, Mouse

Available applications

Enzyme Immunoassay (E), Radioimmunoassay (R), Western blot / Immunoblot (WB)

Background of cAMP / cyclic AMP antibody

Cyclic adenosine monophosphate (cAMP) plays a key role as an intracellular second messenger for transduction events that follow a number of extracellular signals. The G-Protein Coupled Receptors (GPCR) is the largest family of cell surface receptors. They can be activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, and other physiological signaling molecules. Typically, the binding of the ligands to its receptor resulting in the activation of G-proteins, in return, activates the effector adenylyl cyclase evoking the production of cAMP. The activation of a protein kinase by cAMP results in the phosphorylation of substrate proteins. Currently successful drugs in marketing have been developed to target these receptors. Among the GPCRs, ~367 receptors are potential drug development targets, but only about 20 have been used to generate therapeutically and commercially successful drugs so far. Because the involvement of cAMP can amplify the response of the ligand binding, the second messenger cAMP has been largely employed to monitor the activation of the GPCR to facilitate the therapeutic drug discovery.

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

cAMP / cyclic AMP antibody

cAMP / cyclic AMP Mouse IgG1 9H4C4 Ascites E
0.1 ml / €440.00
  Acris Antibodies GmbH

cAMP / cyclic AMP antibody

cAMP / cyclic AMP Rabbit Aff - Purified E
0.1 ml / €370.00
  Acris Antibodies GmbH

cAMP / cyclic AMP antibody

cAMP / cyclic AMP Rabbit Serum Hu R
0.1 ml / €440.00
  Acris Antibodies GmbH

cAMP / cyclic AMP antibody

cAMP / cyclic AMP Rabbit Serum Hu R
20 µl / €170.00
  Acris Antibodies GmbH

cAMP / cyclic AMP antibody

cAMP / cyclic AMP Sheep IgG Ig Fraction E
1 ml / €580.00
  Acris Antibodies GmbH

cAMP / cyclic AMP antibody

cAMP / cyclic AMP Sheep IgG Ig Fraction E
0.1 ml / €390.00
  Acris Antibodies GmbH

cAMP / cyclic AMP antibody

cAMP / cyclic AMP Rabbit Serum Hu R
0.1 ml / €500.00
  Acris Antibodies GmbH

cAMP / cyclic AMP antibody

cAMP / cyclic AMP Rabbit Serum Hu R
20 µl / €170.00
  Acris Antibodies GmbH

cAMP / cyclic AMP antibody

ELISA Plot : cAMP immorbolized onto plates, followed by addition of stand cAMP. The cAMP monoclonal antibody, clone SPM486 ( Cat # MAB2548 ) was added subsequentially, and visiualized by chromatogenic substrate. Each samples were triplicated. IC50 was then calculated. Mouse SPM486 Hu, Ms, Rt E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

cAMP / cyclic AMP antibody

cAMP / cyclic AMP Sheep IgG E
0.1 ml / €560.00
  Abnova Taiwan Corp.

cAMP / cyclic AMP antibody

cAMP / cyclic AMP Rabbit IgG E
0.1 ml / €400.00
  Abnova Taiwan Corp.

11 Item(s)

per page
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