Cannabinoid receptor 1 antibody

Principal name

Cannabinoid receptor 1 antibody

Alternative names for Cannabinoid receptor 1 antibody

CB1, CB-R, CNR1, CNR, CANN6

SwissProt ID

O02777 (Felca), P20272 (Rat), P21554 (Human), P47746 (Mouse)

Gene ID

1268 (CNR1), 25248 (Cnr1)

Available reactivities

Hu (Human), Rt (Rat), Amph (Amphibian), Chk (Chicken), Fi (Fish), Ms (Mouse), Prim (Primate), Mky (Monkey), Can (Canine), Fe (Feline), Bov (Bovine), Por (Porcine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection))

Background of Cannabinoid receptor 1 antibody

Canbinoids have been used in eastern medicine for many years as pain relievers. ?-tetrahydrocanbinol (THC), the major psychoactive compound in marijua and hashish, has been shown to interact with two specific canbinoid receptors: canbinoid receptor 1 (CB1 Receptor or CB1R) and canbinoid receptor 2 (CB2 Receptor or CB2R). The canbinoid receptors can be distinguished by their amino acid sequences, sigling mechanisms, and tissue distributions. Both receptors belong to the G-protein-coupled receptor (GPCR) superfamily. CB1R was shown to modulate several Ca2+ and K+ ion channels. CB1R is primarily expressed in the central nervous system. However, expression of CB1R is also detected in the peripheral termils, in non-neurol peripheral tissues such as uterus, testes, spleen, as well as in cells of the immune system. CB1R is implicated in many cellular functions such as neurotransmitter release, pain relief, cancer, and obesity. Growth inhibition of tumor cells was demonstrated following mixed CB1R/CB2R agonist treatment in both prostate and non-melanoma skin cancers. Through their interaction with CB1R, canbinoid compounds stimulate appetite for sweets and palatable foods in particular, making CB1R an attractive therapeutic target for the treatment of obesity and eating disorders.

General readings

General / background references:Tsou K et al. Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience 83:393-411 (1998). PubMed PMID: 9460749
Twitchell W et al. Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons. J Neurophysiol 78:43-50 (1997). PubMed PMID: 9242259
1. Mulhern, M. L., Madson, C. J., Danford, A., Ikesugi, K., Kador, P. F., and Shinohara, T. (2006) The Unfolded Protein Response in Lens Epithelial Cells from Galactosemic Rat Lenses, 47, 3951-3959.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cannabinoid receptor 1 antibody

TA302439 (1µg/ml) staining of human brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Fe, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cannabinoid receptor 1 antibody

Western blot analysis of rat brain membrane proteins: 1. Anti-Cannabinoid Receptor 1 (extracellular) antibody, (1:200). 2. Anti-Cannabinoid Receptor 1 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Cannabinoid receptor 1 antibody

Western blot analysis of extracts of mouse brain tissue lines, using CNR1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cannabinoid receptor 1 antibody

Anti-CNR1 / CB1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Chk, Hu, Mky, Por
50 µg / €379.00
  OriGene Technologies, Inc.

Cannabinoid receptor 1 antibody

WB Suggested Anti-CNR1 Antibody; Titration: 1.0 ug/ml; Positive Control: COLO205 Whole Cell Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Cannabinoid receptor 1 (Isoforma a) antibody

TA348978 (0.3 ug/ml) staining of A549 (A) and NIH3T3 (B) lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cannabinoid receptor 1 antibody

Immunohistochemical analysis with paraffin-embedded mouse brain tissue using Cannabinoid receptor 1 antibody (Cat.-No. AP01265PU-N). Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Cannabinoid receptor 1 antibody

Cannabinoid receptor 1 Rabbit Serum Hu, Ms, Rt C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Cannabinoid receptor 1 (3rd Cytopl. Dom.) antibody

Immunohistochemical staining of brain neurons using anti-CB1 antibody SP4084P Rabbit Aff - Purified Elephant, Fe, Hst, Hu, Mky, Ms, Prim, Rt, Shrew ICC/IF, P
50 µg / €470.00
  Acris Antibodies GmbH

Cannabinoid receptor 1 (C-term) antibody

Immunohistochemical staining of Brain (Neuron) using anti- CNR1 antibody SP4085P Rabbit Aff - Purified Av, Bear, Bov, Bt, Can, Eq, Fe, Hu, Mky, Ms, Op, Por, Prim, Rt, Xen ICC/IF, P
50 µg / €470.00
  Acris Antibodies GmbH

Cannabinoid receptor 1 antibody

CNR1 polyclonal antibody (A01), Lot # 051012JC01 Western Blot analysis of CNR1 expression in MCF-7 ( Cat # L046V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Cannabinoid receptor 1 antibody

Western Blot analysis of CNR1 expression in transfected 293T cell line (H00001268-T01) by CNR1 MaxPab polyclonal antibody.

Lane 1: CNR1 transfected lysate(51.92 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Cannabinoid receptor 1 antibody

Detection limit for recombinant GST tagged CNR1 is approximately 0.1ng/ml as a capture antibody. Mouse IgG2b 2F9 Purified Hu, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Cannabinoid receptor 1 antibody

Detection limit for recombinant GST tagged CNR1 is approximately 0.1ng/ml as a capture antibody. Mouse IgG2a 1F9 Purified Hu, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Cannabinoid receptor 1 antibody

HEK293 overexpressing CNR1 and probed with CNR1 polyclonal antibody ( Cat # PAB6876 ) ( mock transfection in second lane ), tested by Origene. Goat Hu, Ms E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Cannabinoid receptor 1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CNR1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

Cannabinoid receptor 1 antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CNR1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

Cannabinoid receptor 1 (N-term) antibody

Human COLO205; WB Suggested Anti-CNR1 Antibody. . Titration: 1.0 ug/ml. . Positive Control: COLO205 Whole Cell; CNR1 antibody - N-terminal region (ARP59994_P050) in Human COLO205 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Cannabinoid receptor 1 antibody

Western Blot: Cannabinoid Receptor 1 Antibody [NB100-2427]-HEK293 overexpressing CNR1 (RC218922) and probed with EB06945 (mock transfection in second lane), tested by Origene Goat IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Cannabinoid receptor 1 antibody

Figure 1 shows immunlocalization of rat CB1 transfected into AtT20 cells using NB 300-552. Rabbit Aff - Purified Hu, Rt C, ICC/IF, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

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