Cannabinoid receptor 2 antibody

Principal name

Cannabinoid receptor 2 antibody

Alternative names for Cannabinoid receptor 2 antibody

CB-2, hCB2, CB2, CNR2, CX5

SwissProt ID

P34972 (Human), P47936 (Mouse), Q9QZN9 (Rat)

Gene ID

1269 (CNR2), 6126975 (IPR001926), 57302 (Cnr2)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Mky (Monkey), Gorilla, Bt (Bat), Can (Canine), Eq (Equine), Hst (Hamster)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of Cannabinoid receptor 2 antibody

Canbinoids have been used as pain relievers in eastern medicine for many years. To date, two specific canbinoid receptors have been identified: the Canbinoid Receptor 1 (CB1R) and the Canbinoid Receptor 2 (CB2R). The canbinoid receptors can be distinguished by their amino acid sequence, sigling mechanisms and tissue distribution. Both receptors belong to the G-protein coupled receptor superfamily and are coupled to Gi/0 G protein. The CB2R is highly expressed in cells of the immune system such as macrophages, lymphocytes tural killer cells and mast cells but has also been shown to be expressed, by both, in situ-hybridization and in immunohistochemistry, in spleen, thymus, and pancreas. CB2R expression in brain is still much less characterized than that of CB1R. Recently, it was demonstrated that CB2R is expressed in brain and might have role in controlling fundamental processes such as proliferation and survival of neural cells. Overexpression of CB2R was reported in several cancers such as prostate, glioma and acute myeloid leukemias.In human astrocytoma a direct relationship between CB2R expression and tumor maligncy was demonstrated. Activation of CB2R, in vivo, by its agonist JWH-133, completely blocked cell growth. In C6 glioma it was shown that activation of the CB2R by JWH-133 resulted in the interlization of only the CB2R, and not CB1R leading to apoptosis of the cells. This may well be a new approach for the treatment of glioma.

General readings

General / background references:Tsou K et al. Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience 83:393-411 (1998). PubMed PMID: 9460749
Twitchell W et al. Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons. J Neurophysiol 78:43-50 (1997). PubMed PMID: 9242259

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cannabinoid receptor 2 antibody

Anti-CNR2 / CB2 antibody IHC of human tonsil, germinal center and mantle zone. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Bt, Can, Eq, Gorilla, Hst, Hu, Mky, Ms, Rt
50 µg / €345.00
  OriGene Technologies, Inc.

Cannabinoid receptor 2 antibody

TA303061 (2µg/ml) staining of Jurkat lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cannabinoid receptor 2 antibody

Western blot analysis of extracts from COLO205 cells, using CNR2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cannabinoid receptor 2 (N-term Extracell. Dom.) antibody

Anti-CNR2 / CB2 antibody IHC of human tonsil, germinal center and mantle zone. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Elephant, Hu, Mky, Prim P
50 µg / €345.00
  OriGene Technologies, Inc.

Cannabinoid receptor 2 antibody

Anti-CNR2 / CB2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 11 ug/ml. Rabbit IgG Purified Gorilla, Hu, Mky ICC/IF
50 µg / €345.00
  OriGene Technologies, Inc.

Cannabinoid receptor 2 antibody

Anti-CNR2 / CB2 antibody IHC of human germinal center and mantle zone. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Hu, Mky
50 µg / €345.00
  OriGene Technologies, Inc.

Cannabinoid receptor 2 (C-term) antibody

CB2 Antibody (C-term) (Cat. #TA324364) western blot analysis in A431 cell line lysates (35ug/lane).This demonstrates the CB2 antibody detected the CB2 protein (arrow). Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Cannabinoid receptor 2 antibody

Western blot analysis of HL-60 (human Promyelocytic leukemia) (lanes 1and 2) and MCF-7 (human adenocarcinoma, mammary gland) (lanes 3 and 4) cell line lysates: 1, 3. Anti-Cannabinoid Receptor 2 (extracellular) antibody, (1:200). 2, 4. Anti-Cannabinoid Receptor 2 (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Cannabinoid receptor 2 antibody

Western blot analysis of RBL (lanes 1,3), C6 (lanes 2,4) and rat lung (lanes 5,6) lysates: 1,2,5. Anti-Cannabinoid Receptor 2 antibody, (1:200). 3,4,6. Anti-Cannabinoid Receptor 2 antibody, preincubated with the control peptide antigen. Rabbit Purified Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Cannabinoid receptor 2 antibody

Western blot (WB) analysis of CB2 antibody (Cat.-No.: AP01212PU-N) in extracts from COLO205 cells. Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Cannabinoid receptor 2 antibody

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Cannabinoid receptor 2 antibody

Western Blot analysis of CNR2 expression in transfected 293T cell line by CNR2 monoclonal antibody (M01), clone 3C7.

Lane 1: CNR2 transfected lysate(39.7 KDa).
Lane 2: Non-transfected lysate. Mouse IgG1 3C7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Cannabinoid receptor 2 antibody

CNR2 polyclonal antibody ( Cat # PAB6877 ) ( 2 µg/ml ) staining of Jurkat lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Cannabinoid receptor 2 antibody

Western blot analysis of extracts from COLO205 cells, using CNR2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

Cannabinoid receptor 2 antibody

Western blot analysis of extracts from COLO205 cells, using CNR2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

Cannabinoid receptor 2 antibody

NB 100-2458 (2ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Cannabinoid receptor 2 antibody

Cannabinoid receptor 2 Rabbit Aff - Purified Hu ICC/IF, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Cannabinoid receptor 2 antibody

Immunohistochemistry-Paraffin: Cannabinoid Receptor II Antibody [NBP1-88175] - Immunohistochemical staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Cannabinoid receptor 2

Cannabinoid receptor 2 Human
2 µg / €450.00
  Abnova Taiwan Corp.

Cannabinoid receptor 2

Cannabinoid receptor 2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

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