CAPD3 antibody

Principal name

CAPD3 antibody

Alternative names for CAPD3 antibody

NCAPD3, KIAA0056, hCAP-D3, Condensin-2 complex subunit D3, Non-SMC condensin II complex subunit D3

SwissProt ID

P42695 (Human), Q6ZQK0 (Mouse)

Gene ID

23310 (NCAPD3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of CAPD3 antibody

Smad3 is a 50 kDa member of a family of proteins that act as key mediators of TGF beta superfamily signaling in cell proliferation, differentiation and development. The Smad family is divided into three subclasses: receptor regulated Smads, activin/TGF beta receptor regulated (Smad2 and 3) or BMP receptor regulated (Smad 1, 5, and 8); the common partner, (Smad4) that functions via its interaction to the various Smads; and the inhibitory Smads, (Smad6 and 7). Activated Smad3 oligomerizes with Smad4 upon TGF beta stimulation and translocates as a complex into the nucleus, allowing its binding to DNA and transcription factors. Phosphorylation of the two TGF beta dependent serines 423 and 425 in the C terminus of Smad3 is critical for Smad3 transcriptional activity and TGF beta signaling.

General readings

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010)
Takemoto, A., et al. Nat. Struct. Mol. Biol. 16(12):1302-1308(2009)
Lapointe, J., et al. Am. J. Surg. Pathol. 32(2):205-209(2008)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Seshadri, S., et al. BMC Med. Genet. 8 SUPPL 1, S15 (2007)

3 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CAPD3 (C-term) antibody

Western blot analysis of CAPD3 Antibody (C-term) Cat.-No AP52823PU-N in K562 cell line lysates (35ug/lane). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CAPD3 antibody

Immunoperoxidase of monoclonal antibody to KIAA0056 on formalin-fixed paraffin-embedded human breast cancer tissue.[antibody concentration 2ug/ml] Mouse IgG1 1D5 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.


Catalog No.    

NCAPD3 overexpression lysate

NCAPD3 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

3 Item(s)

per page
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