CAPZB antibody

Principal name

CAPZB antibody

Alternative names for CAPZB antibody

CapZ beta, CAPZ-B, F-actin-capping protein subunit beta

SwissProt ID

A0PFK7 (Pig), P47756 (Human), P47757 (Mouse), P79136 (Bovin), Q5XI32 (Rat)

Gene ID

338052 (CAPZB), 832

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Can (Canine), Por (Porcine), Prim (Primate)

Available hosts

Guinea Pig, Goat, Mouse, Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CAPZB antibody

F-actin-capping-protein subunit beta (CapZ beta) belongs to the F-actin capping protein family, which are characteristic heterodimers, consisting of an α subunit (31-36 kDa) and a β subunit (28-32 kDa), that cap the barbed end of actin filaments within all eukaryotes. Their ability to bind the actin filaments is in a manner independent of Ca2++ and requires the C-terminal end of both subunits for optimal binding. F-actin capping protein subunit beta is contained within the Z-discs of striated muscle, where it functions to inhibit the polymerization and depolymerization of actin. Within vertebrates, there are three isoforms for each of F-actin capping protein subunit beta’s subunits. While there is almost nothing known regarding the β3 subunit, the β1 and β2 isoforms each have distinct roles. The isoform β2 is predominantly expressed in non-muscle cells and is found in intercalated discs and the cell periphery, but is not observed at Z-discs. Isoform β1 is more greatly expressed in striated muscle and is localized at the Z-discs. It also contains the COOH-terminal extension necessary for capping the actin.

General readings

Hart MC & Cooper JA Vertebrate isoforms of actin capping protein beta have distinct functions In vivo. J Cell Biol 147:1287-98 (1999). PubMed PMID: 10601341

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CAPZB (C-term) antibody

TA302723 staining (1µg/ml) of Hela lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CAPZB (192-272) antibody

Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 1H1 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

CAPZB antibody

Sample (50 ug of whole cell lysate). A: Mouse brain. 12% SDS PAGE. TA308374 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CAPZB antibody

WB Suggested Anti-Capzb Antibody; Titration: 1.0 ug/ml; Positive Control: Rat Small Intestine Rabbit IgG Purified Hu, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CAPZB (C-term) antibody

(LEFT) Western blot analysis of CAPZB Antibody (C-term) (AP17177PU-N) in mouse brain tissue lysates (35 µg/lane). CAPZB (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of CAPZB (arrow) using rabbit polyclonal CAPZB Antibody (C-term) (AP17177PU-N). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the CAPZB gene (Lane 2). Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CAPZB (N-term) antibody

Western blot analysis of CAPZB (arrow) using rabbit polyclonal CAPZB Antibody (N-term) (AP17178PU-N). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the CAPZB gene (Lane 2). Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CAPZB (N-term) antibody

CAPZB Guinea Pig Serum Bov WB
0.1 ml / €360.00
  Acris Antibodies GmbH

CAPZB antibody

CAPZB Goat Purified Bov, Hu, Ms WB
0.1 mg / €690.00
  Acris Antibodies GmbH

CAPZB antibody

CAPZB Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CAPZB antibody

CAPZB MaxPab polyclonal antibody. Western Blot analysis of CAPZB expression in human placenta. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CAPZB antibody

Immunoperoxidase of monoclonal antibody to CAPZB on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 1.5 ug/ml] Mouse IgG2a 1H1 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CAPZB antibody

CAPZB monoclonal antibody (M03), clone 4H8 Western Blot analysis of CAPZB expression in HeLa ( Cat # L013V1 ). Mouse IgG2a 4H8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CAPZB antibody

CAPZB polyclonal antibody ( Cat # PAB6046 ) staining ( 1 µg/ml ) of HeLa lysate ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu, Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CAPZB antibody

NB 100-814 staining (1µg/ml) of Hela lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat IgG Aff - Purified Hu, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

CAPZB antibody

Immunohistochemistry-Paraffin: CAPZB Antibody [NBP1-85922] - Immunohistochemical staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CAPZB

CAPZB Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

CAPZB

CAPZB Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

CAPZB

CAPZB Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CAPZB

CAPZB Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CAPZB 293T Cell Transient Overexpression Lysate(Denatured)

CAPZB 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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