Carabin antibody

Principal name

Carabin antibody

Alternative names for Carabin antibody

TBC1D10C, TBC1 domain family member 10C

SwissProt ID

Q8C9V1 (Mouse), Q8IV04 (Human)

Gene ID

374403 (TBC1D10C)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), Eq (Equine), Rb (Rabbit)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C)

Background of Carabin antibody

Antigen binding by the T-cell receptor (TCR) is one of the critical first steps in the immune response, triggering a cascade of signaling pathways that ultimately lead to T-cell activation. Screening a yeast two-hybrid screen of a human T-cell cDNA library with calcineurin, a protein phosphatase involved in multiple signaling pathways including T-cell activation, resulted in the identification of Carabin, a member of the TBC1 domain family of proteins, as a calcineurin-binding protein. Unlike other members of the TBC1 domain protein family which are thought to have a role in regulating cell growth and differentiation, further experiments demonstrated that Carabin is part of a negative regulatory loop for the intracellular TCR signaling pathway as well as an inhibitor of the Ras signaling pathway, suggesting that Carabin may also mediate crosstalk between calcineurin and Ras. Carabin antibody does not recognize TBC1D10A or TBC1D10B. Carabin is known to exist in multiple isoforms.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Carabin antibody

TA303203 (2µg/ml) staining of Human Spleen lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Purified Can, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Carabin (C-term) antibody

Western blot analysis of Carabin in Daudi cell lysate with Carabin antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Carabin (N-term) antibody

Western blot analysis of Carabin in human spleen tissue lysate with Carabin antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Carabin antibody

WB Suggested Anti-TBC1D10C Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Carabin antibody

WB Suggested Anti-TBC1D10C Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Thymus Rabbit IgG Purified Bov, Can, Eq, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Carabin (N-term) antibody

Formalin fixed, paraffin embedded human spleen with Rabbit anti Human Carabin (AP05728PU-N) following heat mediated antigen retrieval using sodium citrate buffer (pH6.0). Rabbit IgG Purified Hu, Ms P, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

Carabin Control Peptide

Carabin
50 µg / €160.00
  Acris Antibodies GmbH

Carabin Control Peptide

Carabin
50 µg / €160.00
  Acris Antibodies GmbH

Carabin antibody

TBC1D10C polyclonal antibody ( Cat # PAB7529 ) ( 2 µg/ml ) staining of human spleen lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Ms, Rt E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Carabin antibody

Immunohistochemistry of TBC1D10C in human spleen tissue with TBC1D10C polyclonal antibody ( Cat # PAB13276 ) at 2.5 µg/ml. Rabbit Hu, Ms P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Carabin antibody

Immunohistochemistry of TBC1D10C in human spleen tissue with TBC1D10C polyclonal antibody ( Cat # PAB13277 ) at 2.5 µg/ml. Rabbit Hu, Ms P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Carabin antibody

Human Jurkat; WB Suggested Anti-TBC1D10C Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Jurkat cell lysate; TBC1D10C antibody - N-terminal region (ARP55893_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Carabin antibody

Human Thymus; WB Suggested Anti-TBC1D10C Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Thymus; TBC1D10C antibody - N-terminal region (ARP55894_P050) in Human Thymus cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

Carabin antibody

Immunohistochemistry-Paraffin: carabin Antibody [NBP1-76806] - Human spleen tissue with Carabin antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Carabin antibody

Immunohistochemistry-Paraffin: carabin Antibody [NBP1-76807] - Human spleen tissue with Carabin antibody at 2.5 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Carabin

Carabin Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Carabin

Carabin Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

TBC1D10C overexpression lysate

TBC1D10C overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

18 Item(s)

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