Carboxypeptidase B2 antibody

Principal name

Carboxypeptidase B2 antibody

Alternative names for Carboxypeptidase B2 antibody

CPB2, Carboxypeptidase U, TAFI, CPU, pCPB, Thrombin-activable fibrinolysis inhibitor, Plasma carboxypeptidase B

SwissProt ID

Q2KIG3 (Bovin), Q96IY4 (Human), Q9EQV9 (Rat), Q9JHH6 (Mouse)

Gene ID

1361 (CPB2), 56373 (Cpb2), 113936

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), ELISA (capture) (E(capture)), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Paraffin Sections (P)

Background of Carboxypeptidase B2 antibody

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms.

General readings

Ricart,J.M., (2008) Br. J. Haematol. 141 (5), 716-719

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Carboxypeptidase B2 antibody

  Rabbit polyclonal anti-CPB2 antibody  
Western blot analysis of extracts from HepG2 cells, using CPB2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Carboxypeptidase B2 antibody

  Rabbit Polyclonal Anti-CPB2 Antibody  
WB Suggested Anti-CPB2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Human heart Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Carboxypeptidase B2 antibody

  CPB2 mouse monoclonal antibody, clone OTI3D5 (formerly 3D5)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-CPB2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA807474) Mouse IgG1 OTI3D5 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Carboxypeptidase B2 antibody

Western blot analysis of CPB2 antibody (Center E134) (AP17235PU-N) in Jurkat cell line lysates (35 µg/lane). CPB2 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Carboxypeptidase B2 antibody

Western blot analysis of extracts from HepG2 cells, using CPB2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Assay Biotech

Carboxypeptidase B2 antibody

Western blot analysis of extracts from HepG2 cells, using CPB2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €330.00
  Assay Biotech

Carboxypeptidase B2 antibody

Carboxypeptidase B2 Mouse IgG2a 13D5 Purified Hu E, E(capture)
1 mg / €480.00
  HyTest Ltd.

Carboxypeptidase B2 antibody

Carboxypeptidase B2 Mouse IgG1 13H4 Purified Hu E, E(detection), WB
1 mg / €480.00
  HyTest Ltd.

Carboxypeptidase B2 antibody

Carboxypeptidase B2 Mouse IgG1 19E2 Purified Hu E, E(detection), WB
1 mg / €480.00
  HyTest Ltd.

CRISPR

Catalog No. Species Donor Vector  

CPB2 - human gene knockout kit via CRISPR

CPB2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CPB2 - human gene knockout kit via CRISPR

CPB2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CPB2 - human gene knockout kit via CRISPR

CPB2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CPB2 - human gene knockout kit via CRISPR

CPB2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cpb2 - mouse gene knockout kit via CRISPR

Cpb2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cpb2 - mouse gene knockout kit via CRISPR

Cpb2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cpb2 - mouse gene knockout kit via CRISPR

Cpb2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cpb2 - mouse gene knockout kit via CRISPR

Cpb2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Carboxypeptidase B2 (transcript variant 1)

  Recombinant protein of human carboxypeptidase B2 (plasma) (CPB2), transcript variant 1  
Carboxypeptidase B2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Carboxypeptidase B2

Carboxypeptidase B2 Human Purified Plasma
0.1 mg / €1,900.00
  HyTest Ltd.

Lysates

Catalog No.    

CPB2 overexpression lysate

CPB2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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