Carboxypeptidase N catalytic chain antibody
Principal name
Carboxypeptidase N catalytic chain antibody
Alternative names for Carboxypeptidase N catalytic chain antibody
CPN, CPN1, ACBP, Kininase-1, Serum carboxypeptidase N, Anaphylatoxin inactivator, Plasma carboxypeptidase B, Lysine carboxypeptidase, Arginine carboxypeptidase, SCPN, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit
Ncbi ID
9606, NP_001299, NP_001299.1, NM_001308, NP_109628.1, NM_030703, NM_053526
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)
Background of Carboxypeptidase N catalytic chain antibody
Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
General readings
Skidgel,R.A. (2007) Int. Immunopharmacol. 7 (14), 1888-1899









Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA313681 | Carboxypeptidase N catalytic chain antibody |
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Rabbit polyclonal anti-CPN1 (carboxypeptidase N, polypeptide 1) antibody | |||||||
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Rabbit | IgG | Purified | Hu | E, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
TA340008 | Carboxypeptidase N catalytic chain antibody |
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Rabbit Polyclonal Anti-CPN1 Antibody | |||||||
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Rabbit | IgG | Purified | Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze | P, WB |
50 µg /
€360.00
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|
OriGene Technologies, Inc. | |||||||
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TA340009 | Carboxypeptidase N catalytic chain antibody |
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Rabbit Polyclonal Anti-CPN1 Antibody | |||||||
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Rabbit | IgG | Purified | Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze | WB |
50 µg /
€360.00
|
|
OriGene Technologies, Inc. | |||||||
AP01465PU-N | Carboxypeptidase N catalytic chain antibody |
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Rabbit | Aff - Purified | Hu | WB |
0.1 mg /
€350.00
|
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Acris Antibodies GmbH | |||||||
AP51053PU-N | Carboxypeptidase N catalytic chain (Center) antibody |
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Rabbit | Ig | Purified | Hu | P, WB |
0.4 ml /
€370.00
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|
Acris Antibodies GmbH | |||||||
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C14963-1 | Carboxypeptidase N catalytic chain antibody |
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Rabbit | Aff - Purified | Hu | E, WB |
50 µg /
€230.00
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Assay Biotech | |||||||
C14963-2 | Carboxypeptidase N catalytic chain antibody |
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Rabbit | Aff - Purified | Hu | E, WB |
0.1 mg /
€330.00
|
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Assay Biotech |
CRISPR
Catalog No. | Species | Donor Vector | |
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KN206606 | CPN1 - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN206606BN | CPN1 - human gene knockout kit via CRISPR |
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Human | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN206606LP | CPN1 - human gene knockout kit via CRISPR |
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Human | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN206606RB | CPN1 - human gene knockout kit via CRISPR |
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Human | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN303760 | Cpn1 - mouse gene knockout kit via CRISPR |
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Mouse | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN303760BN | Cpn1 - mouse gene knockout kit via CRISPR |
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Mouse | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN303760LP | Cpn1 - mouse gene knockout kit via CRISPR |
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Mouse | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN303760RB | Cpn1 - mouse gene knockout kit via CRISPR |
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Mouse | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. |
Proteins & Growth Factors
Catalog No. | Species | Pres. | Purity | Source | |
---|---|---|---|---|---|
TP760866 | Carboxypeptidase N catalytic chain (full length, N-term HIS tag) |
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Purified recombinant protein of Human carboxypeptidase N, polypeptide 1 (CPN1), full length, with N-terminal HIS tag, expressed in E. coli, 50ug | |||||
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Human | > 80 % Preparation: . Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
50 µg /
€199.00
|
|
OriGene Technologies, Inc. |
Lysates
Catalog No. | ||
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LY420016 | CPN1 overexpression lysate |
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0.1 mg /
€295.00
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|
OriGene Technologies, Inc. |
Human Lenti ORF Particles
Catalog No. | ||
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RC206606L2V | Lenti ORF particles, CPN1 (mGFP-tagged) - Human carboxypeptidase N, polypeptide 1 (CPN1), 200 uL, >10^7 TU/mL |
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200 µl /
€1,082.00
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|
OriGene Technologies, Inc. | ||
Mouse Lenti ORF Particles
Catalog No. | ||
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MR207305L2V | Lenti ORF particles, Cpn1 (GFP-tagged) - Mouse carboxypeptidase N, polypeptide 1 (Cpn1), 200 uL, >10^7 TU/mL |
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200 µl /
€1,092.00
|
|
OriGene Technologies, Inc. | ||
MR207305L1V | Lenti ORF particles, Cpn1 (Myc-DDK-tagged) - Mouse carboxypeptidase N, polypeptide 1 (Cpn1), 200 uL, >10^7 TU/mL |
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200 µl /
€979.00
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OriGene Technologies, Inc. | ||