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Carboxypeptidase N catalytic chain antibody

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Principal name

Carboxypeptidase N catalytic chain antibody

Alternative names for Carboxypeptidase N catalytic chain antibody

CPN, CPN1, ACBP, Kininase-1, Serum carboxypeptidase N, Anaphylatoxin inactivator, Plasma carboxypeptidase B, Lysine carboxypeptidase, Arginine carboxypeptidase, SCPN, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit

SwissProt ID

P15169 (Human), Q2KJ83 (Bovin), Q9EQV8 (Rat), Q9JJN5 (Mouse)

Gene ID

1369 (CPN1), 93721 (Cpn1), 365466

Ncbi ID

9606, NP_001299, NP_001299.1, NM_001308, NP_109628.1, NM_030703, NM_053526

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Dros (Drosophila), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of Carboxypeptidase N catalytic chain antibody

Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Skidgel,R.A. (2007) Int. Immunopharmacol. 7 (14), 1888-1899

AP01465PU-N - Carboxypeptidase N catalytic chain
Western blot (WB) analysis of CPN cat antibody (Cat.-No.: AP01465PU-N) in extracts from RAW264.7 cell
ARP51939_P050 - Carboxypeptidase N catalytic chain
Human Heart; Heart; CPN1 antibody - middle region (ARP51939_P050) in Human Heart cells using Immunohistochemistry
ARP51939_P050 - Carboxypeptidase N catalytic chain
Transfected 293T; WB Suggested Anti-CPN1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Transfected 293T; CPN1 antibody - middle region (ARP51939_P050) in Transfected 293T cells using Western Blot
ARP51940_P050 - Carboxypeptidase N catalytic chain
Transfected 293T; WB Suggested Anti-CPN1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Transfected 293T; CPN1 antibody - middle region (ARP51940_P050) in Transfected 293T cells using Western Blot
C14963-1 - Carboxypeptidase N catalytic chain
Western blot analysis of extracts from RAW264.7 cells, using CPN1 Antibody. The lane on the right is treated with the synthesized peptide.
AP51053PU-N - Carboxypeptidase N catalytic chain
Formalin fixed and paraffin embedded human liver tissue stained with CPN1 Antibody (Center) Cat.-No AP51053PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of CPN1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
AP51053PU-N - Carboxypeptidase N catalytic chain
Western blot analysis of CPN1 (arrow) using CPN1 Antibody (Center) Cat.-No AP51053PU-N. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CPN1 gene.
CPA1264-100ul - Carboxypeptidase N catalytic chain
Western blot analysis of Carboxypeptidase N 1 expression in HepG2 (A); HEK293T (B) whole cell lysates.
TP760866 - Carboxypeptidase N catalytic chain
TA313681 - Carboxypeptidase N catalytic chain
Western blot analysis of extracts from RAW264.7 cells, using CPN1 antibody.The lane on the right is treated with the synthesized peptide.
TA340008 - Carboxypeptidase N catalytic chain
WB Suggested Anti-CPN1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Transfected 293T
TA340008 - Carboxypeptidase N catalytic chain
Heart
TA340009 - Carboxypeptidase N catalytic chain
WB Suggested Anti-CPN1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Transfected 293T

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Carboxypeptidase N catalytic chain antibody
  Rabbit polyclonal anti-CPN1 (carboxypeptidase N, polypeptide 1) antibody  
Western blot analysis of extracts from RAW264.7 cells, using CPN1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Carboxypeptidase N catalytic chain antibody
  Rabbit Polyclonal Anti-CPN1 Antibody  
WB Suggested Anti-CPN1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze P, WB
50 µg / €360.00
  OriGene Technologies, Inc.
+1 additional image

Carboxypeptidase N catalytic chain antibody
  Rabbit Polyclonal Anti-CPN1 Antibody  
WB Suggested Anti-CPN1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €360.00
  OriGene Technologies, Inc.

Carboxypeptidase N catalytic chain antibody
Western blot (WB) analysis of CPN cat antibody (Cat.-No.: AP01465PU-N) in extracts from RAW264.7 cell Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Carboxypeptidase N catalytic chain (Center) antibody
Formalin fixed and paraffin embedded human liver tissue stained with CPN1 Antibody (Center) Cat.-No AP51053PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of CPN1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH
+1 additional image

Carboxypeptidase N catalytic chain antibody
Western blot analysis of extracts from RAW264.7 cells, using CPN1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Assay Biotech

Carboxypeptidase N catalytic chain antibody
Western blot analysis of extracts from RAW264.7 cells, using CPN1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

CPN1 - human gene knockout kit via CRISPR
CPN1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CPN1 - human gene knockout kit via CRISPR
CPN1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CPN1 - human gene knockout kit via CRISPR
CPN1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CPN1 - human gene knockout kit via CRISPR
CPN1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cpn1 - mouse gene knockout kit via CRISPR
Cpn1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cpn1 - mouse gene knockout kit via CRISPR
Cpn1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cpn1 - mouse gene knockout kit via CRISPR
Cpn1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cpn1 - mouse gene knockout kit via CRISPR
Cpn1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Carboxypeptidase N catalytic chain (full length, N-term HIS tag)
  Purified recombinant protein of Human carboxypeptidase N, polypeptide 1 (CPN1), full length, with N-terminal HIS tag, expressed in E. coli, 50ug  
Carboxypeptidase N catalytic chain Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CPN1 overexpression lysate
CPN1 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CPN1 (mGFP-tagged) - Human carboxypeptidase N, polypeptide 1 (CPN1), 200 uL, >10^7 TU/mL
Lenti ORF particles, CPN1 (mGFP-tagged) - Human carboxypeptidase N, polypeptide 1 (CPN1), 200 uL, >10^7 TU/mL  
200 µl / €1,082.00
  OriGene Technologies, Inc.
 

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cpn1 (GFP-tagged) - Mouse carboxypeptidase N, polypeptide 1 (Cpn1), 200 uL, >10^7 TU/mL
Lenti ORF particles, Cpn1 (GFP-tagged) - Mouse carboxypeptidase N, polypeptide 1 (Cpn1), 200 uL, >10^7 TU/mL  
200 µl / €1,092.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Cpn1 (Myc-DDK-tagged) - Mouse carboxypeptidase N, polypeptide 1 (Cpn1), 200 uL, >10^7 TU/mL
Lenti ORF particles, Cpn1 (Myc-DDK-tagged) - Mouse carboxypeptidase N, polypeptide 1 (Cpn1), 200 uL, >10^7 TU/mL  
200 µl / €979.00
  OriGene Technologies, Inc.
 

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22 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. CRISPR (8)
  2. Human Lenti ORF Particle (1)
  3. Lysate (1)
  4. Mouse Lenti ORF Particle (2)
  5. Primary Antibody (7)
  6. Protein | Growth Factor (1)
  7. Rat Lenti ORF Particle (2)
Clonality
  1. Polyclonal (7)
Target
  1. Carboxypeptidase N catalytic chain (8)
Property
  1. Center (1)
Reactivity
  1. Human (Hu) (7)
  2. Bovine (Bov) (2)
  3. Canine (Can) (2)
  4. Equine (Eq) (2)
  5. Guinea Pig (GP) (2)
  6. Mouse (Ms) (2)
  7. Porcine (Por) (2)
  8. Rabbit (Rb) (2)
  9. Rat (Rt) (2)
  10. Zebrafish (Ze) (2)
Applications
  1. Western blot / Immunoblot (WB) (7)
  2. Enzyme Immunoassay (E) (3)
  3. Paraffin Sections (P) (2)
Presentation
  1. Purified (4)
  2. Aff - Purified (3)
Host
  1. Rabbit (7)
Images
  1. 1 image (8)
Images: Applications
  1. Western blot / Immunoblot (WB) (7)
  2. IHC (1)
  3. Paraffin Sections (P) (1)
Species (Protein)
  1. Human (1)
Source
  1. E. coli (1)
Species (CRISPR)
  1. Human (4)
  2. Mouse (4)
Donor Vector
  1. GFP-Puro (2)
  2. Luciferase-Puro (2)
  3. RFP-BSD (2)
  4. mBFP-Neo (2)
Manufacturer
  1. Acris - OriGene (20)
  2. Assay Biotech (2)
Service
  • OriGene EU
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  • D-32052 Herford
  • Germany
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  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
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  • orders: ordering@acris-online.de
 
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