CARD15 / NOD2 antibody

Principal name

CARD15 / NOD2 antibody

Alternative names for CARD15 / NOD2 antibody

IBD1, Nucleotide-binding oligomerization domain-containing protein 2,Caspase recruitment domain-containing protein 15, Inflammatory bowel disease protein 1

SwissProt ID

Q8K3Z0 (Mouse), Q9HC29 (Human)

Gene ID

64127 (NOD2), 257632

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat, Rat

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), ELISA (detection) (E(detection))

Background of CARD15 / NOD2 antibody

Nod2, also known as caspase recruitment domain-containing protein 15, CARD15, and inflammatory bowel disease protein 1, is a monocyte-specific cytoplasmic protein containing two N-terminal caspase recruitment domains (CARD domains), and multiple leucine-rich repeats with a predicted molecular weight 115 kD. Alternative initiation produces two isoforms of Nod2. Nod2 is thought to confer responsiveness to intracellular bacterial lipopolysaccharide (LPS), and defects in Nod2 have been linked to several diseases including Blau syndrome, Crohns's disease, and ulcerative colitis. Knock-out animals has been shown to have dramatically altered responses to bacterial pathogens in the gut. Nod2 binds to the receptor interacting kinase 1 protein via CARD-CARD interaction and induces NF-κB and IKK-gamma. 
Structure: Cytoplasmic protein containing two N-terminal caspase recruitment domains (CARD domains), multiple leucine-rich repeats, predicted molecular weight 115 kD. Alternative initiation produces two isoforms.
Distribution: Monocyte-specific.
Function: Confers responsiveness to intracellular bacterial lipopolysaccharide (LPS). Binds to RIP2 via CARD-CARD interaction and induces NF-κB and IKK-gamma. Defects in Nod1 are associated with Blau syndrome, Crohn's disease, and ulcerative colitis.
Interaction: RIP2, CARD12.

Items 1 to 20 of 35 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CARD15 / NOD2 antibody

TA303142 (0.1µg/ml) staining of Human Peripheral Blood Mononucleocyte lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CARD15 / NOD2 (N-term) antibody

Western blot analysis of NOD2 in Jurkat cell lysate with NOD2 antibody at (A) 1, (B) 2 and (C) 4 ug/mL. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CARD15 / NOD2 (C-term) antibody

Western blot analysis of NOD2 in HeLa cell lysate with NOD2 antibody at (A) 2 and (B) 4 ug/mL. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CARD15 / NOD2 antibody

Immunoblot of HEK 293T cell control lysate (lane 1) and HEK 293T cells transfected with Mouse NOD2 (lane 2).  The blots were probed with 2 ug/ml of Anti-Mouse NOD2 Purified followed by Anti-Rat HRP and visualized by chemiluminescence. Rat 26mNOD2 Purified Ms WB
50 µg / €120.00
  OriGene Technologies, Inc.

CARD15 / NOD2 antibody

Cell extract from MCF-7 cells transfected with either human Nod1 (Lane 1) or human Nod2 (Lane 2) was resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal anti-Nod2 antibody (clone NOD-15). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system. The NOD-15 antibody is specific for human Nod2 and does not cross-react with human Nod1. Mouse IgG2a NOD-15 Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CARD15 / NOD2 antibody

Western Blot: NOD2 Antibody [TA336664] - Detection of NOD2 in 20ug of NOD2 transfected 293T cell lysate using NB 500-253.  ECL detection in 15 seconds. Rabbit Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CARD15 / NOD2 antibody

Mouse Lymph Node: Formalin-Fixed, Paraffin-Embedded (FFPE) Rat IgG1 26mNOD2 Aff - Purified Ms P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CARD15 / NOD2 antibody

Cell extract from MCF-7 cells transfected with either human Nod1 (Lane 1) or human Nod2 (Lane 2) was resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal anti-Nod2 antibody (clone NOD-15). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system. The NOD-15 antibody is specific for human Nod2 and does not cross-react with human Nod1. Mouse IgG2a NOD-15 Aff - Purified Hu WB
25 µg / €220.00
  Acris Antibodies GmbH

CARD15 / NOD2 (C-term) antibody

Immunocytochemical staining of HeLa cells with Rabbit anti Human NOD2 (AP05557PU-N) Rabbit IgG Purified Hu ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CARD15 / NOD2 (C-term) antibody

Immunocytochemical staining of HeLa cells with Rabbit anti Human NOD2 (AP05557PU-N) Rabbit IgG Purified Hu ICC/IF, WB
50 µg / €300.00
  Acris Antibodies GmbH

CARD15 / NOD2 antibody

Small intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CARD15 / NOD2 (C-term) antibody

Small intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CARD15 / NOD2 Control Peptide

CARD15 / NOD2
50 µg / €160.00
  Acris Antibodies GmbH

CARD15 / NOD2 Control Peptide

CARD15 / NOD2
50 µg / €160.00
  Acris Antibodies GmbH

CARD15 / NOD2 antibody

CARD15 / NOD2 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CARD15 / NOD2 antibody

CARD15 / NOD2 Rabbit Serum Hu IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

CARD15 / NOD2 antibody

Western Blot analysis of NOD2 expression in transfected 293T cell line (H00064127-T01) by NOD2 MaxPab polyclonal antibody.

Lane 1: NOD2 transfected lysate(114.40 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CARD15 / NOD2 antibody

Formalin-fixed, paraffin-embedded normal human colon stained for NOD2 expression. Using NOD2 polyclonal antibody ( Cat # PAB0265 ) at 1 : 2000. A, tissue core from a colon tissue microarray. A1, high magnification of A. Hematoxylin-eosin counterstain. Rabbit Hu C, IP, P, WB
50 µl / €400.00
  Abnova Taiwan Corp.

CARD15 / NOD2 antibody

NOD2 polyclonal antibody ( Cat # PAB7102 ) ( 0.1 µg/ml ) staining of human peripheral blood mononucleocyte lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CARD15 / NOD2 antibody

Western blot analysis of NOD2 in NOD2 transfected HEK 293T ( Bosc 23 ) cell lysate with NOD2 polyclonal antibody ( Cat# PAB12097 ). Rabbit Hu WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

Items 1 to 20 of 35 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn