CARD6 antibody

Principal name

CARD6 antibody

Alternative names for CARD6 antibody

Caspase recruitment domain-containing protein 6

SwissProt ID

Q9BX69 (Human)

Gene ID

84674 (CARD6)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Immunoprecipitation (IP)

Background of CARD6 antibody

CARDs (caspase recruitment domain) are homotypic protein-protein interaction motifs belonging to the death domain (DD)-fold superfamily (reviewed in Werts et al, 2006). Homotypic interactions among CARD-containing proteins can occur with various proteins, including the inactive zymogen forms of caspases which have N-terminal pro-domains containing complementary CARDs. These interactions can result in the formation of multiprotein complexes, leading to protease cleavage and caspase activation. Most proteins containing a CARD are involved in signal transduction pathways that regulate apoptosis, adaptive immunity, or innate immunity including NF-kB activation and inflammation. There is a large number of CARD containing proteins, and the unique function of each remains to be fully elucidated.
CARD6 is a CARD-containing protein with a domain structure that does not appear to be shared by any other protein (Stehlik et al, 2003). CARD6 has been found to associate with microtubules, and is structurally and potentially functionally related to the superfamily of interferon (INF)-inducible GTPases (Dufner, 2006). INF-inducible GTPases belong to a growing family of host defense proteins that confer cell immunity. Specifically, is thought that CARD6 may act as a pattern recognition receptor that combats pathogens in a cell-autonomous manner.

General readings

Stehlik C, Hayashi H, Pio F, Godzik A, Reed JC.
CARD6 is a modulator of NF-kB activation by Nod1- and Cardiak-mediated pathways.
J Biol Chem. 2003 May 29 [Epub ahead of print]
PMID: 12775719

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CARD6 (N-term) antibody

TA305815 (5ug/ml) staining of paraffin embedded Human Pancreas. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Aff - Purified Hu P
0.1 mg / €325.00
  OriGene Technologies, Inc.

CARD6 antibody

Western blot analysis of extracts from HeLa cells, using CARD6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CARD6 antibody

Western blot analysis on HeLa cell lysate using CARD6 Antibody Rabbit IgG Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CARD6 antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using CARD6 antibody (Cat.-No. AP06035PU-N). Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CARD6 (2-15) antibody

Pancreas: Formalin-Fixed Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Hu, Mky, Prim E, P
50 µg / €470.00
  Acris Antibodies GmbH

CARD6 antibody

CARD6 Mouse IgG2a 2H8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CARD6 antibody

CARD6 Rabbit Hu C, IP, P
50 µl / €390.00
  Abnova Taiwan Corp.

CARD6 antibody

CARD6 Rabbit Hu C, IP, P
50 µl / €390.00
  Abnova Taiwan Corp.

CARD6 antibody

CARD6 Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

CARD6 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CARD6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

CARD6 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CARD6 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

CARD6 antibody

Immunohistochemical analysis of CARD6 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CARD6 antibody

Immunohistochemical analysis of CARD6 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CARD6 antibody

Immunohistochemical analysis of CARD6 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CARD6 antibody

NB100-1221(5ug/ml) staining of paraffin embedded Human Pancreas. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat IgG Aff - Purified Hu E, P
0.1 mg / €400.00
  Novus Biologicals Inc.

CARD6 antibody

Immunohistochemistry: CARD6/CINCIN1 Antibody [NB100-91682] -  CARD6/CINCIN1 (A2) antibody [NB100-91682] - in paraffin-embedded  human breast carcinoma tissue Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CARD6

CARD6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CARD6

CARD6 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CARD6 overexpression lysate

CARD6 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

19 Item(s)

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