Cardiac Troponin C antibody

Principal name

Cardiac Troponin C antibody

Alternative names for Cardiac Troponin C antibody

TNNC1, TNNC, TN-C

SwissProt ID

P02591 (Rabit), P09860 (Chick), P19123 (Mouse), P63315 (Bovin), P63316 (Human), P63317 (Pig)

Gene ID

7134 (TNNC1), 509486, 21924 (Tnnc1), 100347570 (LOC100347570), 100156435, 7137 (TNNI3)

Available reactivities

Hu (Human), Rb (Rabbit), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (capture) (E(capture)), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunoprecipitation (IP)

Background of Cardiac Troponin C antibody

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

General / background references:Sarko J & Pollack CV Cardiac troponins. J Emerg Med 23:57-65 (2002). PubMed PMID: 12217473
Gomes AV et al. The role of troponins in muscle contraction. IUBMB Life 54:323-33 (2002). PubMed PMID: 12665242
Hamm CW Acute coronary syndromes. The diagnostic role of troponins. Thromb Res 103 Suppl 1:S63-9 (2001). PubMed PMID: 11567671
Labugger R et al. Extensive troponin I and T modification detected in serum from patients with acute myocardial infarction. Circulation 102:1221-6 (2000). PubMed PMID: 10982534
Wu AH et al. Characterization of cardiac troponin subunit release into serum after acute myocardial infarction and comparison of assays for troponin T and I. American Association for Clinical Chemistry Subcommittee on cTnI Standardization. Clin Chem 44:1198-208 (1998). PubMed PMID: 9625043
Katrukha AG et al. Troponin I is released in bloodstream of patients with acute myocardial infarction not in free form but as complex. Clin Chem 43:1379-85 (1997). PubMed PMID: 9267317

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cardiac Troponin C antibody

Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TNNC1 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.0) at 120C for 3 min, UM800096)(1:200) Mouse IgG2a UMAB204 Purified Hu P
0.1 ml / €468.00
  OriGene Technologies, Inc.

UltraMAB

Cardiac Troponin C antibody

Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TNNC1 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.0) at 120C for 3 min, UM800096)(1:200) Mouse IgG2a UMAB204 Purified Hu P
30 µl / €140.00
  OriGene Technologies, Inc.

UltraMAB

Cardiac Troponin C antibody

Predicted band size: 18 kDa . Positive control: Stomach tissue lysate. Recommended dilution: 1/500-2000. (Gel: 12%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cardiac Troponin C antibody

Western blot analysis of extracts of various cell lines, using TNNC1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cardiac Troponin C antibody

Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TNNC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804479) Mouse IgG2a OTI5H3 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cardiac Troponin C antibody

Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TNNC1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804501) Mouse IgG1 OTI8F8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cardiac Troponin C antibody

Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TNNC1 Mouse monoclonal antibody. (TA804630; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Mouse IgG1 OTI9D4 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cardiac Troponin C antibody

Immunohistochemical staining of paraffin-embedded Human adult heart tissue using anti-TNNC1 Mouse monoclonal antibody. (TA804824; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Mouse IgG1 OTI1H5 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cardiac Troponin C antibody

Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a n.a Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Cardiac Troponin C antibody

Cardiac Troponin C Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Cardiac Troponin C antibody

Immunoperoxidase of monoclonal antibody to TNNC1 on formalin-fixed paraffin-embedded human heart. [antibody concentration 3ug/ml] Mouse IgG1 1F8-A9 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Cardiac Troponin C antibody

Cardiac Troponin C Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

Cardiac Troponin C antibody

Cardiac Troponin C Mouse IgG2a 1A2 Purified Hu, Rb E, E(capture), WB
1 mg / €380.00
  HyTest Ltd.

Cardiac Troponin C antibody

Cardiac Troponin C Mouse IgG1 7B9 Purified Hu E, E(detection), WB
1 mg / €380.00
  HyTest Ltd.

Cardiac Troponin C antibody

Cardiac Troponin C Mouse IgG2b 12G3 Purified Hu E, WB
1 mg / €380.00
  HyTest Ltd.

Cardiac Troponin C (in vitro) antibody

Cardiac Troponin C Mouse IgG1 7B9cc Purified Hu E, E(detection), WB
1 mg / €380.00
  HyTest Ltd.

Cardiac Troponin C antibody

Cardiac Troponin C Mouse IgG2a 1A2 Hu E, WB
0.2 mg / €290.00
  Novus Biologicals Inc.

Cardiac Troponin C antibody

Cardiac Troponin C Mouse IgG1 7B9 Hu E, WB
0.2 mg / €290.00
  Novus Biologicals Inc.

Cardiac Troponin C antibody

Cardiac Troponin C Mouse IgG2b 12G3 Hu E, IP, WB
0.2 mg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Cardiac Troponin C

Cardiac Troponin C Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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