CASC3 antibody

Principal name

CASC3 antibody

Alternative names for CASC3 antibody

MLN51, Protein barentsz, Protein MLN 51 homolog, Cancer susceptibility candidate gene 3 protein, Metastatic lymph node protein 51

SwissProt ID

O15234 (Human), Q8K3W3 (Mouse), Q8K3X0 (Rat)

Gene ID

22794 (CASC3), 192160 (Casc3)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of CASC3 antibody

The multiprotein exon junction complex (EJC) is deposited on mRNAs upstream of exon–exon junctions as a consequence of pre-mRNA splicing. In mammalian cells, this complex serves as a key modulator of spliced mRNA metabolism. MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer. The function of MLN51 in mammals remains elusive. Its fly homolog, named barentsz, as well as the proteins mago nashi and tsunagi have been shown to be required for proper oskar mRNA localization to the posterior pole of the oocyte. Magoh and Y14, the human homologs of mago nashi and tsunagi, are core components of the exon junction complex (EJC). The EJC is assembled on spliced mRNAs and plays important roles in post-splicing events including mRNA export, nonsense-mediated mRNA decay, and translation. Human MLN51 is an RNA-binding protein present in ribonucleo-protein complexes.

12 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CASC3 antibody

WB Suggested Anti-CASC3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 12500; Positive Control: ACHN cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CASC3 (C-term) antibody

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CASC3 Antibody (C-term) (AP13976PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CASC3 antibody

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CASC3 Antibody (AP13977PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CASC3 antibody

CASC3 polyclonal antibody (A01), Lot # 060501JCS1 Western Blot analysis of CASC3 expression in HeLa ( Cat # L013V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CASC3 pTyr181 antibody

CASC3 Rabbit Hu E, WB
0.4 ml / €400.00
  Abnova Taiwan Corp.

CASC3 antibody

Human ACHN; WB Suggested Anti-CASC3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: ACHN cell lysate; CASC3 antibody - N-terminal region (ARP54817_P050) in Human ACHN cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CASC3 antibody

Western Blot: CASC3 Antibody [NBP1-30321]-Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells.  Antibodies: Affinity purified rabbit anti-CASC3 used for IP at 3 mcg/mg lysate.  CASC3 was also immunoprecipitated by another rabbit anti-CASC3 antibody, which recognizes a downstream epitope. Rabbit Hu IP, P
0.1 ml / €440.00
  Novus Biologicals Inc.

CASC3 antibody

Western Blot: CASC3 Antibody [NBP1-56306] - This Anti-CASC3 antibody was used in Western Blot of ACHN       tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

CASC3 antibody

Immunohistochemistry-Paraffin: CASC3 Antibody [NBP1-88515] -  staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CASC3

CASC3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CASC3

CASC3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CASC3

CASC3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

12 Item(s)

per page
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