CASK antibody

Principal name

CASK antibody

Alternative names for CASK antibody

Lin-2 homolog, LIN2, Peripheral plasma membrane protein CASK, Calcium/calmodulin-dependent serine protein kinase

SwissProt ID

O14936 (Human), O70589 (Mouse), Q62915 (Rat)

Gene ID

8573 (CASK), 29647 (Cask)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Xen (Xenopus), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CASK antibody

CASK (calmodulin sensitive kinase) is a ~112kDa member of the membrane associated quanylate kinase (MAGUK) protein family. It is an adaptor protein with a calcium/calmodulin-dependent protein kinase domain, a SH3 domain, aguanylate kinase homology domain (GUK) and a PDZ domain. CASK links transmembrane proteins to the cytoskeleton and signaling molecules. In particular, CASK binds to Neurexin to stabilize pre- and post-synaptic structrures (1). While most of CASK proteins are cytoplasmic, a portion of the protein enters the nucleus, where it acts as a transcriptional co-activator.
Manifesting the importance of CASK, transgenic mice with insertional mutations die within 24 hours of births. CASK is also localized in the nuclei of basal keratinocytes in newborn rodent skin and developing hair follicles. It may play a role in wound healing.

General readings

Martinez-Estrada OM et al. Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial caco-2 cells. J Biol Chem 276:9291-6 (2001). PubMed PMID: 11120739
Hata Y et al. Synaptic PDZ domain-containing proteins. Neurosci Res 32:1-7 (1998). PubMed PMID: 9831248

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CASK antibody

Western blot analysis of extracts of various cell lines, using CASK antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

CASK (C-term) antibody

Western blot analysis of CASK (arrow) using Cask Antibody (C-term) (Cat.#TA302217). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CASK gene (Lane 2) (Origene Technologies). Rabbit Ig Purified Hu, Ms P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CASK antibody

Rat Cask Antibody (Center) (Cat. #TA325180) western blot analysis in rat brain tissue lysates (35ug/lane).This demonstrates the Rat Cask antibody detected the Rat Cask protein (arrow). Rabbit IgG Purified Hu, Ms, Rt WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

CASK antibody

Western blot analysis on rat brain membrane tissues using a 1:1000 dilution of the antibody Mouse IgG1 S56A-50 Purified Hu, Ms, Rt, Xen, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CASK (N-term) antibody

Western blot analysis of CASK in mouse brain tissue lysate with CASK antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CASK antibody

Adult rat brain immunohistochemistry Mouse IgG1 K56A/50 Supernatant Hu, Ms, Rt, Xen, Ze C, IP, WB
5 ml / €320.00
  Antibodies Incorporated

NeuroMab

CASK antibody

Adult rat brain immunohistochemistry Mouse IgG1 K56A/50 Purified Hu, Ms, Rt, Xen, Ze C, IP, WB
0.1 ml / €380.00
  Antibodies Incorporated

NeuroMab

CASK (318-415) antibody

CASK Mouse IgG1 S56A-50 Purified Hu, Ms, Rt, Xen, Ze C, ICC/IF, IP, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

CASK (N-term) Control Peptide

Western blot analysis in mouse brain tissue lysate with CASK antibody Cat.-No. AP55443PU-Nat 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
50 µg / €160.00
  Acris Antibodies GmbH

CASK antibody

CASK Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

CASK antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with CASK polyclonal antibody ( Cat # PAB2776 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu, Ms E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

CASK antibody

Western Blot: CASK Antibody [NB300-321] - Western blot of CASK on AtT20 cell lysate using NB300-321. Rabbit Aff - Purified Hu, Ms, Rt C, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

CASK antibody

CASK Mouse IgG1 S56A-50 Purified Hu, Ms, Rt, Xen, Ze C, IP, P, WB
0.1 mg / €450.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CASK (transcript variant 1)

CASK Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CASK overexpression lysate

CASK overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

15 Item(s)

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