Alternative names for CASKIN1 antibody
Caskin-1, KIAA1306, CASK-interacting protein 1
Enzyme Immunoassay (E), Western blot / Immunoblot (WB)
Background of CASKIN1 antibody
CASKIN1 Antibody: Calcium/calmodulin-dependent serine protein kise (CASK) is a conserved multi-domain scaffolding protein involved in brain development, sypse formation, and establishment of cell polarity. CASKINs (CASK interacting proteins) interact with CASK and is thought to play a role in CASK function, specifically by coupling CASK to distinct downstream effectors. CASKIN1 is a multidomain protein containing six N-termil ankyrin repeats, one SH3 domain, and two sterile alpha motif domains followed by a long proline-rich sequence and a short conserved C-termil domain. CASKIN1 coassembles with CASK on the cytoplasmic tail of neurexin 1, suggesting that CASKIN and CASK coat the cytoplasmic tails of neurexins and other cell-surface proteins.
Tabuchi K, Biederer T, Butz S, et al. CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with CASKIN1, a novel CASK-binding protein. J. Neurosci. 2002; 22:4264-73.