Caspase-1 antibody

Principal name

Caspase-1 antibody

Alternative names for Caspase-1 antibody

CASP-1, CASP1, IL1BC, IL1BCE, ICE, p45, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme

SwissProt ID

P29452 (Mouse), P29466 (Human), P43527 (Rat), P89116 (Spofr), Q9MZV7 (Canfa)

Gene ID

834 (CASP1), 12362 (Casp1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine)

Available hosts

Rabbit, Mouse, Rat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E), Functional assay (FN), ELISA (detection) (E(detection)), Flow Cytometry (F)

Background of Caspase-1 antibody

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms. [provided by RefSeq]. Transcript Variant: This variant (gamma) has multiple differences in the coding region but the translation remains in frame, compared to variant alpha. Variant gamma encodes a protein lacking an internal segment, as compared to isoform alpha. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

General / background references:Enari M et al. Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature 375:78-81 (1995). PubMed PMID: 7536900

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Caspase-1 antibody

Western blot analysis of Caspase-1 expression in Rat liver tissue lysate using Caspase-1 Antibody Cat.-No AP00006PU-N Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, IP, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Caspase-1 antibody

Western Blot: Caspase 1 Antibody (14F468) [TA336409] - analysis of Caspase-1 using a Caspase-1 monoclonal antibody. Human HeLa (A) and mouse NIH3T3 lysate probed with Caspase-1 antibody at 0.5 ug/ml and 2 ug/ml, respectively. Mouse IgG1 14F468 Purified Hu, Ms C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Caspase-1 antibody

Human placenta stained with Anti-Caspase 1 antibody Rabbit Purified Hu, Ms, Rt P
0.5 ml / €360.00
  Acris Antibodies GmbH

Caspase-1 antibody

Human placenta stained with Anti-Caspase 1 antibody Rabbit Purified Hu, Ms, Rt P
1 ml / €440.00
  Acris Antibodies GmbH

Caspase-1 antibody

Human placenta stained with Anti-Caspase 1 antibody Rabbit Purified Hu, Ms, Rt P
0.1 ml / €180.00
  Acris Antibodies GmbH

Caspase-1 (C-term) antibody

Western blot analysis of Caspase-1 in human heart cell lysate with Caspase-1 antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Caspase-1 antibody

Western blot analysis of Caspase-1 in HeLa cell lysate with Caspase-1 antibody (IN) at (A) 0.5, (B) 1, and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Caspase-1 antibody

Western blot analysis of extracts from K562 cells and HepG2 cells, using Caspase 1 (Cleaved-Asp210) antibody (#TA312620).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Caspase-1 antibody

Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 1 (Cleaved-Asp210) antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Caspase-1 antibody

Western blot analysis of extracts from rat eye cells, using CASP1 (p20, Cleaved-Asn120) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Caspase-1 antibody

Western blot analysis of extracts from COS7 cells, using Caspase 1 (p10, Cleaved-Ala317) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Caspase-1 antibody

Western blot analysis of Hela cell using TA323203(CASP1 Antibody) at dilution 1/150 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Caspase-1 antibody

Predicted cell location: Cytoplasm . Positive control: Human pancreatic cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human pancreatic cancer tissue using CASP1 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Caspase-1 antibody

Western blot analysis of extracts of various cell lines, using CASP1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Caspase-1 antibody

Western Blot: Caspase 1 Antibody [TA336408] - analysis of Caspase-1 using a polyclonal antibody. Human HeLa lysate probed with Caspase-1 antibody at 0.5 ug/ml. Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Caspase-1 antibody

Western blot analysis of Caspase 1 expression in 293 cells Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Caspase-1 antibody

Western Blot analysis: MCF7 (Lane 1) and Jurkat (Lane 2) cell extracts were resolved by electrophoresis, transferred to nitrocellulose and probed with anti-Capsase-1 Antibody Cat.-No AM33084PU (Clone 5B10). Proteins were visualized using a goat anti-rat secondary antibody conjugated to HRP and a chemiluminescence system. Rat IgG2a 5B10 Purified Hu P, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

Caspase-1 antibody

Western Blot analysis: MCF7 (Lane 1) and Jurkat (Lane 2) cell extracts were resolved by electrophoresis, transferred to nitrocellulose and probed with anti-Capsase-1 Antibody Cat.-No AM33084PU (Clone 5B10). Proteins were visualized using a goat anti-rat secondary antibody conjugated to HRP and a chemiluminescence system. Rat IgG2a 5B10 Purified Hu P, WB
25 µg / €240.00
  Acris Antibodies GmbH

Caspase-1 Control Peptide

Caspase-1 Purified
50 µg / €190.00
  Acris Antibodies GmbH

Caspase-1 antibody

Immunohistochemistry (IHC) analyzes of Caspase 1 antibody (Cat.-No.: AP06610PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

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